Janus Henderson Group
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Janus Henderson Group’s Praxis Precision Medicines PRAX Stock Holding History

Janus Henderson Group’s Portfolio PRAX Stock Details PRAX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$1.11B Buy
3,458,863
+218,777
+7% +$67.7M 0.53% 31
2025
Q4 		$955M Buy
3,240,086
+476,227
+17% +$88.7M 0.43% 43
2025
Q3 		$146M Buy
2,763,859
+230,454
+9% +$11.2M 0.07% 222
2025
Q2 		$107M Buy
2,533,405
+1,026,969
+68% +$39.1M 0.05% 254
2025
Q1 		$58.3M Buy
1,506,436
+576,913
+62% +$36M 0.03% 341
2024
Q4 		$71.6M Buy
929,523
+405,957
+78% +$29.4M 0.04% 320
2024
Q3 		$30.1M Buy
523,566
+141,881
+37% +$7.66M 0.02% 496
2024
Q2 		$15.9M Buy
381,685
+71,626
+23% +$3.38M 0.01% 614
2024
Q1 		$18.9M Buy
+310,059
New +$13.9M 0.01% 571
2022
Q2 		– Sell
-222,263
Closed -$34M – 2662
2022
Q1 		$34M Sell
222,263
-575
-0.3% -$118K 0.02% 609
2021
Q4 		$65.9M Buy
222,838
+4,227
+2% +$1.24M 0.03% 468
2021
Q3 		$60.6M Buy
218,611
+20,045
+10% +$5.44M 0.03% 495
2021
Q2 		$54.4M Buy
198,566
+127,673
+180% +$45.7M 0.02% 550
2021
Q1 		$34.8M Buy
70,893
+11,068
+19% +$7.87M 0.02% 642
2020
Q4 		$49.4M Buy
+59,825
New +$34.9M 0.02% 541

Other funds holding PRAX

OAG
Orbis Allan Gray Hamilton, Bermuda $23.7B AUM 65.43% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
DM
Deerfield Management New York $8.48B AUM 99.04% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
CAM
Cormorant Asset Management Boston, Massachusetts $1.99B AUM 737.95% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Janus Henderson Group's PRAX Position: Q1 2026 in Review

Janus Henderson Group increased its Praxis Precision Medicines (PRAX) stake by 6.8% in Q1 2026, buying an estimated $67.7M and bringing the position to 3,458,863 shares worth $1.11B. The position accounts for 0.53% of the portfolio, ranked #31.

Janus Henderson Group first reported a position in PRAX in Q4 2020 and has held it in 15 quarters since. 289 funds tracked by Wall St. Rank hold PRAX as of Q1 2026.

  • Janus Henderson Group held 3,458,863 shares of Praxis Precision Medicines worth $1.11B as of Q1 2026.
  • Janus Henderson Group bought 218,777 Praxis Precision Medicines shares in Q1 2026, an estimated $67.7M.
  • Praxis Precision Medicines made up 0.53% of Janus Henderson Group's portfolio in Q1 2026, its #31 holding.
  • Janus Henderson Group first reported a position in Praxis Precision Medicines in Q4 2020 and has held it in 15 quarters since.
  • 289 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q1 2026.

Based on Janus Henderson Group's 13F filing for Q1 2026, filed 15 May 2026.