Sphera Funds Management’s Praxis Precision Medicines PRAX Stock Holding History

Sphera Funds Management’s Portfolio PRAX Stock Details PRAX Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	–	Sell	-40,000	Closed	-$11.8M	–	112
2025 Q4	$11.8M	Sell	40,000 -10,000	-20%	-$1.86M	2.28%	9
2025 Q3	$2.65M	Sell	50,000 -50,000	-50%	-$2.42M	0.56%	62
2025 Q2	$4.21M	Hold	100,000	–	–	0.99%	36
2025 Q1	$3.79M	Buy	100,000 +17,000	+20%	+$1.06M	0.87%	34
2024 Q4	$6.39M	Buy	83,000 +43,000	+108%	+$3.11M	1.15%	28
2024 Q3	$2.3M	Sell	40,000 -35,000	-47%	-$1.89M	0.37%	78
2024 Q2	$3.1M	Buy	+75,000	New	+$3.54M	0.42%	68

Other funds holding PRAX

Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return

OAG

Orbis Allan Gray Hamilton, Bermuda $23.7B AUM 65.43% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return

BBA

Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Deerfield Management New York $8.48B AUM 99.04% 1-Year Est. Return

DCM

Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return

CAM

Cormorant Asset Management Boston, Massachusetts $1.99B AUM 737.95% 1-Year Est. Return

Sphera Funds Management's PRAX Position: Q4 2025 in Review

Sphera Funds Management sold out of Praxis Precision Medicines (PRAX) in Q4 2025, closing a stake of 57,901 shares — an estimated $10.8M sold.

Sphera Funds Management first reported a position in PRAX in Q4 2020 and held it in 12 quarters. The position peaked at $11.7M in Q2 2024. 250 funds tracked by Wall St. Rank hold PRAX as of Q4 2025.

Sphera Funds Management reported no remaining Praxis Precision Medicines position as of Q4 2025 after selling out during the quarter.
Sphera Funds Management sold 57,901 Praxis Precision Medicines shares in Q4 2025, an estimated $10.8M.
Sphera Funds Management first reported a position in Praxis Precision Medicines in Q4 2020 and held it in 12 quarters.
Sphera Funds Management's Praxis Precision Medicines position peaked at $11.7M in Q2 2024.
250 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q4 2025.

Based on Sphera Funds Management's 13F filing for Q4 2025, filed 17 Feb 2026.