Jane Street’s Praxis Precision Medicines PRAX Stock Holding History

Jane Street’s Portfolio PRAX Stock Details PRAX Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$14.6M	Sell	43,700 -3,200	-7%	-$1.01M	﹤0.01%	2434
2026 Q1	$15.1M	Sell	46,900 -26,900	-36%	-$8.32M	﹤0.01%	2057
2025 Q4	$21.8M	Buy	73,800 +61,500	+500%	+$11.5M	﹤0.01%	1554
2025 Q3	$652K	Sell	12,300 -5,500	-31%	-$267K	﹤0.01%	7275
2025 Q2	$748K	Sell	17,800 -18,400	-51%	-$701K	﹤0.01%	6162
2025 Q1	$1.37M	Buy	36,200 +18,900	+109%	+$1.18M	﹤0.01%	4995
2024 Q4	$1.33M	Buy	17,300 +3,400	+24%	+$246K	﹤0.01%	4871
2024 Q3	$800K	Buy	+13,900	New	+$751K	﹤0.01%	6315
2023 Q2	–	Sell	-1,000	Closed	-$12.1K	–	9388
2023 Q1	$12.1K	Buy	+1,000	New	+$42.2K	﹤0.01%	8720

Other funds holding PRAX

Jupiter Topco New York $245B AUM

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return

BBA

Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return

OAG

Orbis Allan Gray Hamilton, Bermuda $29.1B AUM 60.8% 1-Year Est. Return

Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Adage Capital Partners Boston, Massachusetts $71.3B AUM 56.8% 1-Year Est. Return

Jane Street's PRAX Position: Q2 2026 in Review

Jane Street opened a new position in Praxis Precision Medicines (PRAX) in Q2 2026: 1,008 shares worth $337K. The stake represents ﹤0.01% of the portfolio and ranks #8953 among its holdings. This is a return to the name: Jane Street previously reported a position in PRAX as recently as Q3 2025.

Jane Street first reported a position in PRAX in Q2 2022 and has held it in 12 quarters since. The position peaked at $2.87M in Q1 2024. 309 funds tracked by Wall St. Rank hold PRAX as of Q2 2026.

Jane Street held 1,008 shares of Praxis Precision Medicines worth $337K as of Q2 2026.
Praxis Precision Medicines was a new Jane Street position in Q2 2026.
Praxis Precision Medicines made up ﹤0.01% of Jane Street's portfolio in Q2 2026, its #8953 holding.
Jane Street first reported a position in Praxis Precision Medicines in Q2 2022 and has held it in 12 quarters since.
Jane Street's Praxis Precision Medicines position peaked at $2.87M in Q1 2024.
309 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q2 2026.

Based on Jane Street's 13F filing for Q2 2026, filed 14 Aug 2026.