Citadel Advisors
SEPN

Citadel Advisors’s Septerna Inc SEPN Stock Holding History

Citadel Advisors’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$2.74M Buy
+81,800
New +$2.32M ﹤0.01% 5854
2026
Q1 		– Sell
-11,900
Closed -$332K – 14575
2025
Q4 		$332K Sell
11,900
-3,100
-21% -$74K ﹤0.01% 9920
2025
Q3 		$282K Buy
15,000
+3,100
+26% +$40.7K ﹤0.01% 10518
2025
Q2 		$126K Buy
11,900
+4,500
+61% +$37.1K ﹤0.01% 11120
2025
Q1 		$42.8K Buy
+7,400
New +$84.5K ﹤0.01% 12469

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

Citadel Advisors's SEPN Position: Q2 2026 in Review

Citadel Advisors opened a new position in Septerna Inc (SEPN) in Q2 2026: 6,350 shares worth $213K. The stake represents ﹤0.01% of the portfolio and ranks #11930 among its holdings. This is a return to the name: Citadel Advisors previously reported a position in SEPN as recently as Q4 2025.

Citadel Advisors first reported a position in SEPN in Q4 2024 and has held it in 4 quarters since. The position peaked at $9.27M in Q4 2024. 154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • Citadel Advisors held 6,350 shares of Septerna Inc worth $213K as of Q2 2026.
  • Septerna Inc was a new Citadel Advisors position in Q2 2026.
  • Septerna Inc made up ﹤0.01% of Citadel Advisors's portfolio in Q2 2026, its #11930 holding.
  • Citadel Advisors first reported a position in Septerna Inc in Q4 2024 and has held it in 4 quarters since.
  • Citadel Advisors's Septerna Inc position peaked at $9.27M in Q4 2024.
  • 154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on Citadel Advisors's 13F filing for Q2 2026, filed 14 Aug 2026.