|
1
|
RA Capital Management
Boston,
Massachusetts
|
$467M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$297M
|
+$250M
|
+7,735,085
|
+61,570%
|
|
|
3
|
Nextech Invest
Zurich,
Switzerland
|
$155M
|
–
|
–
|
–
|
|
|
4
|
Janus Henderson Group
London,
|
$149M
|
+$30.9M
|
+955,147
|
+33%
|
|
|
5
|
Alta Partners Management Company
Jackson,
Wyoming
|
$146M
|
–
|
–
|
–
|
|
|
6
|
Farallon Capital Management
San Francisco,
California
|
$137M
|
+$49M
|
+1,514,000
|
+73%
|
|
|
7
|
TCG Crossover Management
Palo Alto,
California
|
$124M
|
+$11.4M
|
+350,877
|
+12%
|
|
|
8
|
Commodore Capital
New York
|
$94.8M
|
-$29.1M
|
-900,000
|
-27%
|
|
|
9
|
|
$84.9M
|
+$4.26M
|
+131,506
|
+6%
|
|
|
10
|
Paradigm Biocapital Advisors
New York
|
$78.7M
|
+$66.5M
|
+2,054,991
|
New
|
|
|
11
|
BVF Inc
San Francisco,
California
|
$75.7M
|
-$4.9M
|
-151,469
|
-7%
|
|
|
12
|
Caligan Partners
New York
|
$48.9M
|
+$10.8M
|
+332,711
|
+35%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$46.6M
|
+$15.1M
|
+466,615
|
+62%
|
|
|
14
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$43.1M
|
+$36.5M
|
+1,125,970
|
New
|
|
|
15
|
5AM Venture Management
San Francisco,
California
|
$39.4M
|
–
|
–
|
–
|
|
|
16
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$37.8M
|
+$31.5M
|
+971,629
|
+6,732%
|
|
|
17
|
Logos Global Management
San Francisco,
California
|
$32.6M
|
+$20.7M
|
+640,000
|
+305%
|
|
|
18
|
Barclays
London,
United Kingdom
|
$31.9M
|
+$24.5M
|
+757,090
|
+992%
|
|
|
19
|
Canaan Partners XI
Menlo Park,
California
|
$28.7M
|
-$85M
|
-2,624,329
|
-78%
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$25.2M
|
+$23.5K
|
+726
|
+0.1%
|
|
|
21
|
Jennison Associates
New York
|
$24.2M
|
+$20.5M
|
+632,432
|
New
|
|
|
22
|
Sio Capital Management
New York
|
$23.2M
|
+$2.57M
|
+79,437
|
+15%
|
|
|
23
|
|
$21.1M
|
+$11.9M
|
+367,947
|
+202%
|
|
|
24
|
Deerfield Management
New York
|
$21M
|
+$17.8M
|
+549,000
|
New
|
|
|
25
|
Balyasny Asset Management
Chicago,
Illinois
|
$13.5M
|
-$15.1M
|
-466,847
|
-57%
|
|
