Nextech Invest’s Tyra Biosciences TYRA Stock Holding History

Nextech Invest’s Portfolio TYRA Stock Details TYRA Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$114M	Sell	3,553,585 -502,276	-12%	-$16.6M	5.39%	4
2026 Q1	$155M	Hold	4,055,861	–	–	10.93%	2
2025 Q4	$107M	Hold	4,055,861	–	–	10.31%	2
2025 Q3	$56.7M	Hold	4,055,861	–	–	8.64%	3
2025 Q2	$38.8M	Hold	4,055,861	–	–	7.35%	3
2025 Q1	$37.7M	Hold	4,055,861	–	–	8.77%	2
2024 Q4	$56.4M	Hold	4,055,861	–	–	9.15%	2
2024 Q3	$95.4M	Hold	4,055,861	–	–	13.39%	2
2024 Q2	$64.9M	Hold	4,055,861	–	–	10.91%	2
2024 Q1	$66.5M	Buy	4,055,861 +1,537,279	+61%	+$25.2M	10.54%	3
2023 Q4	$34.9M	Hold	2,518,582	–	–	6.5%	7
2023 Q3	$34.7M	Hold	2,518,582	–	–	10.51%	3
2023 Q2	$42.9M	Hold	2,518,582	–	–	14.58%	2
2023 Q1	$40.5M	Hold	2,518,582	–	–	16.89%	2
2022 Q4	$19.1M	Hold	2,518,582	–	–	7.62%	3
2022 Q3	$22.1M	Hold	2,518,582	–	–	7.15%	4
2022 Q2	$18M	Hold	2,518,582	–	–	6.07%	5
2022 Q1	$26.9M	Hold	2,518,582	–	–	7.69%	5
2021 Q4	$35.4M	Buy	+2,518,582	New	+$50M	9.34%	4

Other funds holding TYRA

RCM

RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

Jupiter Topco New York $245B AUM

APMC

Alta Partners Management Company Jackson, Wyoming $127M AUM 230.85% 1-Year Est. Return

TCM

TCG Crossover Management Palo Alto, California $4.16B AUM 983.43% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Commodore Capital New York $1.68B AUM 375.52% 1-Year Est. Return

PBA

Paradigm Biocapital Advisors New York $5.34B AUM 380.18% 1-Year Est. Return

Nextech Invest's TYRA Position: Q2 2026 in Review

Nextech Invest reduced its Tyra Biosciences (TYRA) stake by 12% in Q2 2026, selling an estimated $16.6M and leaving 3,553,585 shares worth $114M. The position accounts for 5.39% of the portfolio, ranked #4.

Nextech Invest first reported a position in TYRA in Q4 2021 and has held it in 19 quarters since. The position peaked at $155M in Q1 2026. 169 funds tracked by Wall St. Rank hold TYRA as of Q2 2026.

Nextech Invest held 3,553,585 shares of Tyra Biosciences worth $114M as of Q2 2026.
Nextech Invest sold 502,276 Tyra Biosciences shares in Q2 2026, an estimated $16.6M.
Tyra Biosciences made up 5.39% of Nextech Invest's portfolio in Q2 2026, its #4 holding.
Nextech Invest first reported a position in Tyra Biosciences in Q4 2021 and has held it in 19 quarters since.
Nextech Invest's Tyra Biosciences position peaked at $155M in Q1 2026.
169 funds tracked by Wall St. Rank held Tyra Biosciences as of Q2 2026.

Based on Nextech Invest's 13F filing for Q2 2026, filed 14 Aug 2026.