Fidelity Investments
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Fidelity Investments’s Tyra Biosciences TYRA Stock Holding History

Fidelity Investments’s Portfolio TYRA Stock Details TYRA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$297M Buy
7,747,648
+7,735,085
+61,570% +$250M 0.02% 694
2025
Q4 		$330K Buy
12,563
+34
+0.3% +$624 ﹤0.01% 3234
2025
Q3 		$175K Buy
12,529
+327
+3% +$3.73K ﹤0.01% 3407
2025
Q2 		$117K Sell
12,202
-1,694,946
-99% -$16.1M ﹤0.01% 3549
2025
Q1 		$15.9M Sell
1,707,148
-1,400,822
-45% -$18.1M ﹤0.01% 1754
2024
Q4 		$43.2M Sell
3,107,970
-264,880
-8% -$4.81M ﹤0.01% 1438
2024
Q3 		$79.3M Buy
3,372,850
+26,187
+0.8% +$550K ﹤0.01% 1193
2024
Q2 		$53.5M Sell
3,346,663
-630,545
-16% -$10.9M ﹤0.01% 1292
2024
Q1 		$65.2M Buy
3,977,208
+1,208,512
+44% +$19.8M ﹤0.01% 1217
2023
Q4 		$38.3M Sell
2,768,696
-1,130,131
-29% -$14.6M ﹤0.01% 1392
2023
Q3 		$53.7M Sell
3,898,827
-218,042
-5% -$3.23M ﹤0.01% 1216
2023
Q2 		$70.1M Buy
4,116,869
+968,882
+31% +$14.1M 0.01% 1141
2023
Q1 		$50.6M Sell
3,147,987
-731,136
-19% -$8.7M ﹤0.01% 1260
2022
Q4 		$29.5M Sell
3,879,123
-147,178
-4% -$1.04M ﹤0.01% 1467
2022
Q3 		$35.4M Buy
4,026,301
+58,211
+1% +$532K ﹤0.01% 1382
2022
Q2 		$28.4M Sell
3,968,090
-121,995
-3% -$971K ﹤0.01% 1509
2022
Q1 		$43.8M Buy
4,090,085
+621,254
+18% +$7.37M ﹤0.01% 1451
2021
Q4 		$48.8M Buy
3,468,831
+1,560,172
+82% +$31M ﹤0.01% 1429
2021
Q3 		$33.6M Buy
+1,908,659
New +$36.5M ﹤0.01% 1599

Other funds holding TYRA

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
NI
Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
APMC
Alta Partners Management Company Jackson, Wyoming $151M AUM 296.21% 1-Year Est. Return
FCM
Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return
CC
Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $4.89B AUM 251.12% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return

Fidelity Investments's TYRA Position: Q1 2026 in Review

Fidelity Investments increased its Tyra Biosciences (TYRA) stake by 61,570% in Q1 2026, buying an estimated $250M and bringing the position to 7,747,648 shares worth $297M. The position accounts for 0.02% of the portfolio, ranked #694.

Fidelity Investments first reported a position in TYRA in Q3 2021 and has held it in 19 quarters since. 164 funds tracked by Wall St. Rank hold TYRA as of Q1 2026.

  • Fidelity Investments held 7,747,648 shares of Tyra Biosciences worth $297M as of Q1 2026.
  • Fidelity Investments bought 7,735,085 Tyra Biosciences shares in Q1 2026, an estimated $250M.
  • Tyra Biosciences made up 0.02% of Fidelity Investments's portfolio in Q1 2026, its #694 holding.
  • Fidelity Investments first reported a position in Tyra Biosciences in Q3 2021 and has held it in 19 quarters since.
  • 164 funds tracked by Wall St. Rank held Tyra Biosciences as of Q1 2026.

Based on Fidelity Investments's 13F filing for Q1 2026, filed 15 May 2026.