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Tyra Biosciences

46 hedge funds and large institutions have $268M invested in Tyra Biosciences in 2022 Q4 according to their latest regulatory filings, with 1 funds opening new positions, 17 increasing their positions, 11 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

363% more call options, than puts

Call options by funds: $37K | Put options by funds: $8K

55% more repeat investments, than reductions

Existing positions increased: 17 | Existing positions reduced: 11

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

3.16% less ownership

Funds ownership: 86.67%83.51% (-3.2%)

6% less funds holding

Funds holding: 4946 (-3)

16% less capital invested

Capital invested by funds: $320M → $268M (-$51.9M)

75% less first-time investments, than exits

New positions opened: 1 | Existing positions closed: 4

Holders
46
Holders Change
-3
Holders Change %
-6.12%
% of All Funds
0.74%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
1
Increased
17
Reduced
11
Closed
4
Calls
$37K
Puts
$8K
Net Calls
+$29K
Net Calls Change
+$22K
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$55M
BC
2
Boxer Capital
California
$49M
CPX
3
Canaan Partners XI
California
$33.5M
Fidelity Investments
4
Fidelity Investments
Massachusetts
$29.5M -$1.04M -147,178 -4%
NI
5
Nextech Invest
Switzerland
$19.1M
BI
6
BVF Inc
California
$18.8M
TCM
7
TCG Crossover Management
California
$15.1M +$7.38M +1,043,396 +110%
FFM
8
Fairmount Funds Management
Pennsylvania
$10.8M
FLSM
9
Frazier Life Sciences Management
California
$10.1M
BlackRock
10
BlackRock
New York
$4.98M +$233K +32,993 +5%
Vanguard Group
11
Vanguard Group
Pennsylvania
$4.59M +$31.2K +4,414 +0.7%
PA
12
Perceptive Advisors
New York
$3.76M
WP
13
Woodline Partners
California
$2.27M +$410K +57,917 +24%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$1.93M +$44.1K +6,242 +3%
State Street
15
State Street
Massachusetts
$1.65M -$9.63K -1,362 -0.6%
JP Morgan Chase
16
JP Morgan Chase
New York
$1.51M -$144K -20,340 -9%
SCM
17
Sio Capital Management
New York
$1.16M
LGM
18
Logos Global Management
California
$843K -$116K -16,460 -13%
Northern Trust
19
Northern Trust
Illinois
$804K +$13.9K +1,959 +2%
Charles Schwab
20
Charles Schwab
California
$749K +$16.5K +2,328 +2%
Wellington Management Group
21
Wellington Management Group
Massachusetts
$594K -$49.7K -7,027 -8%
Bank of New York Mellon
22
Bank of New York Mellon
New York
$352K +$50.3K +7,119 +18%
D.E. Shaw & Co
23
D.E. Shaw & Co
New York
$251K -$13.3K -1,881 -5%
Citadel Advisors
24
Citadel Advisors
Florida
$203K -$98.3K -13,902 -34%
JAFL
25
Jay A. Fishman Ltd
Michigan
$167K +$81.3K +11,500 +110%

TYRA Hedge Fund Activity: Q4 2022 in Review

46 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Tyra Biosciences (TYRA) for Q4 2022, worth a combined $268M — down 16% from $320M a quarter earlier.

Sellers outnumbered buyers: 4 funds closed out of TYRA and 1 opened new positions — a net loss of 3 holders — while 11 trimmed existing stakes and 17 added.

The largest buyer was TCG Crossover Management, adding an estimated $7.38M. The largest seller was Janus Henderson Group, exiting entirely with an estimated $12M sold.

  • 46 institutional investors held Tyra Biosciences (TYRA) as of Q4 2022, down from 49 in Q3 2022.
  • Funds reported $268M of Tyra Biosciences stock for Q4 2022, down 16% quarter-over-quarter.
  • 1 fund opened new Tyra Biosciences positions in Q4 2022 and 4 closed out, a net change of -3 holders.
  • The largest Tyra Biosciences buyer in Q4 2022 was TCG Crossover Management, an estimated $7.38M added.
  • The largest Tyra Biosciences seller in Q4 2022 was Janus Henderson Group, an estimated $12M sold.

Based on aggregated 13F filings for Q4 2022.