Tyra Biosciences
TYRA
117 hedge funds and large institutions have $500M invested in Tyra Biosciences in 2025 Q1 according to their latest regulatory filings, with 20 funds opening new positions, 42 increasing their positions, 31 reducing their positions, and 16 closing their positions.
366% more call options, than puts
Call options by funds: $233K | Put options by funds: $50K
35% more repeat investments, than reductions
Existing positions increased: 42 | Existing positions reduced: 31
25% more first-time investments, than exits
New positions opened: 20 | Existing positions closed: 16
4.84% more ownership
Funds ownership: 96.07% → 100.91% (+4.8%)
4% more funds holding
Funds holding: 113 → 117 (+4)
20% less funds holding in top 10
Funds holding in top 10: 5 → 4 (-1)
26% less capital invested
Capital invested by funds: $676M → $500M (-$176M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
VPC
Vestal Point Capital
New York
|
+$24.5M |
| 2 |
KCM
Kynam Capital Management
Princeton,
New Jersey
|
+$24.3M |
| 3 |
CC
Commodore Capital
New York
|
+$12.3M |
| 4 |
Janus Henderson Group
London,
United Kingdom
|
+$12.3M |
| 5 |
TCM
TCG Crossover Management
Palo Alto,
California
|
+$11.8M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BCM
Boxer Capital Management
San Diego,
California
|
-$28.2M |
| 2 |
Fidelity Investments
Boston,
Massachusetts
|
-$18.1M |
| 3 |
Adage Capital Partners
Boston,
Massachusetts
|
-$2.78M |
| 4 |
NCM
Nantahala Capital Management
New Canaan,
Connecticut
|
-$1.39M |
| 5 |
ABG
Ally Bridge Group
New York
|
-$878K |
TYRA Hedge Fund Activity: Q1 2025 in Review
117 of the 7,461 institutional investors tracked by Wall St. Rank reported a position in Tyra Biosciences (TYRA) for Q1 2025, worth a combined $500M — down 26% from $676M a quarter earlier.
Buyers outnumbered sellers: 20 funds opened new TYRA positions and 16 closed out — a net gain of 4 holders — while 42 added to existing stakes and 31 trimmed.
The largest buyer was Vestal Point Capital, adding an estimated $24.5M. The largest seller was Boxer Capital Management, exiting entirely with an estimated $28.2M sold.
- 117 institutional investors held Tyra Biosciences (TYRA) as of Q1 2025, up from 113 in Q4 2024.
- Funds reported $500M of Tyra Biosciences stock for Q1 2025, down 26% quarter-over-quarter.
- 20 funds opened new Tyra Biosciences positions in Q1 2025 and 16 closed out, a net change of +4 holders.
- The largest Tyra Biosciences buyer in Q1 2025 was Vestal Point Capital, an estimated $24.5M added.
- The largest Tyra Biosciences seller in Q1 2025 was Boxer Capital Management, an estimated $28.2M sold.
Based on aggregated 13F filings for Q1 2025.