TYRA icon

Tyra Biosciences
TYRA

Overview Fund Activity

117 hedge funds and large institutions have $500M invested in Tyra Biosciences in 2025 Q1 according to their latest regulatory filings, with 21 funds opening new positions, 42 increasing their positions, 31 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
117
Holders Change
+4
Holders Change %
+3.54%
% of All Funds
1.59%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
21
Increased
42
Reduced
31
Closed
16
Calls
$233K
Puts
$50K
Net Calls
+$183K
Net Calls Change
+$213K

Top Buyers

1
VPC
Vestal Point Capital
New York
+$17.6M
2
KCM
Kynam Capital Management
New Jersey
+$17.4M
3
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$9.25M
4
CC
Commodore Capital
New York
+$8.84M
5
TCM
TCG Crossover Management
California
+$8.45M

Top Sellers

1
BCM
Boxer Capital Management
California
-$28.2M
2
Fidelity Investments
Fidelity Investments
Massachusetts
-$13M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$2.78M
4
NCM
Nantahala Capital Management
Connecticut
-$1.39M
5
ABG
Ally Bridge Group
New York
-$631K
Name Holding Trade Value Shares
Change 		Shares
Change %
RCM
1
RA Capital Management
Massachusetts
$98.9M – – –
CPX
2
Canaan Partners XI
California
$38.5M -$328K -35,267 -0.8%
APMC
3
Alta Partners Management Company
Wyoming
$37.9M – – –
NI
4
Nextech Invest
Switzerland
$37.7M – – –
BI
5
BVF Inc
California
$36.7M – – –
TCM
6
TCG Crossover Management
California
$27M +$8.45M +909,000 +46%
VPC
7
Vestal Point Capital
New York
$26.8M +$17.6M +1,889,829 +191%
Janus Henderson Group
8
Janus Henderson Group
United Kingdom
$26.3M +$9.25M +946,917 +54%
KCM
9
Kynam Capital Management
New Jersey
$22.4M +$17.4M +1,875,589 +354%
O
10
OrbiMed
New York
$16.3M +$2.63M +282,745 +19%
Fidelity Investments
11
Fidelity Investments
Massachusetts
$15.9M -$13M -1,400,822 -45%
BlackRock
12
BlackRock
New York
$15.8M -$210K -22,587 -1%
Vanguard Group
13
Vanguard Group
Pennsylvania
$11.3M +$98.6K +10,606 +0.9%
FCM
14
Farallon Capital Management
California
$10.6M +$1.33M +142,837 +14%
CC
15
Commodore Capital
New York
$8.84M +$8.84M +950,000 New
5VM
16
5AM Venture Management
California
$8.74M – – –
Geode Capital Management
17
Geode Capital Management
Massachusetts
$4.8M -$12K -1,288 -0.2%
Pictet Asset Management
18
Pictet Asset Management
Switzerland
$4.27M +$977K +105,101 +30%
SCM
19
Sio Capital Management
New York
$3.87M +$1.63M +175,747 +73%
State Street
20
State Street
Massachusetts
$3.85M +$59.7K +6,415 +2%
Millennium Management
21
Millennium Management
New York
$3.76M +$828K +89,024 +28%
Marshall Wace
22
Marshall Wace
United Kingdom
$3.54M +$3.04M +326,623 +604%
Jacobs Levy Equity Management
23
Jacobs Levy Equity Management
New Jersey
$2.81M +$535K +57,556 +24%
Balyasny Asset Management
24
Balyasny Asset Management
Illinois
$2.26M +$2.26M +243,244 New
Northern Trust
25
Northern Trust
Illinois
$2.01M -$58.7K -6,317 -3%
1
2 3 4 5