|
1
|
RA Capital Management
Boston,
Massachusetts
|
$390M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$285M
|
+$38.8M
|
+1,172,865
|
+15%
|
|
|
3
|
|
$139M
|
+$144M
|
+4,352,448
|
New
|
|
|
4
|
Alta Partners Management Company
Jackson,
Wyoming
|
$122M
|
–
|
–
|
–
|
|
|
5
|
Nextech Invest
Zurich,
Switzerland
|
$114M
|
-$16.6M
|
-502,276
|
-12%
|
|
|
6
|
TCG Crossover Management
Palo Alto,
California
|
$104M
|
–
|
–
|
–
|
|
|
7
|
|
$96.8M
|
+$26.9M
|
+814,043
|
+37%
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$88.9M
|
+$59.4M
|
+1,796,506
|
+182%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$68.4M
|
+$30.6M
|
+924,290
|
+76%
|
|
|
10
|
Commodore Capital
New York
|
$59.9M
|
-$19.8M
|
-600,000
|
-24%
|
|
|
11
|
Paradigm Biocapital Advisors
New York
|
$58.4M
|
-$7.49M
|
-226,384
|
-11%
|
|
|
12
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$48.2M
|
+$12.7M
|
+382,477
|
+34%
|
|
|
13
|
BVF Inc
San Francisco,
California
|
$47.1M
|
-$16.5M
|
-500,000
|
-25%
|
|
|
14
|
5AM Venture Management
San Francisco,
California
|
$32.9M
|
–
|
–
|
–
|
|
|
15
|
Deerfield Management
New York
|
$32.5M
|
+$15.5M
|
+468,000
|
+85%
|
|
|
16
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$32.5M
|
+$33.6M
|
+1,016,775
|
New
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$31M
|
+$10.3M
|
+312,252
|
+47%
|
|
|
18
|
Caligan Partners
New York
|
$25.8M
|
-$15.5M
|
-469,982
|
-37%
|
|
|
19
|
Canaan Partners XI
Menlo Park,
California
|
$24M
|
–
|
–
|
–
|
|
|
20
|
Siren LLC
Greenwich,
Connecticut
|
$23.2M
|
+$24M
|
+725,000
|
New
|
|
|
21
|
Sio Capital Management
New York
|
$22.2M
|
+$2.97M
|
+89,876
|
+15%
|
|
|
22
|
Stempoint Capital
New York
|
$20.2M
|
+$14.5M
|
+439,577
|
+228%
|
|
|
23
|
Marshall Wace
London,
United Kingdom
|
$18.6M
|
+$12.7M
|
+385,385
|
+195%
|
|
|
24
|
|
$14.8M
|
-$2.87M
|
-86,857
|
-16%
|
|
|
25
|
Jennison Associates
New York
|
$14.4M
|
-$6M
|
-181,468
|
-29%
|
|
