|
1
|
RA Capital Management
Boston,
Massachusetts
|
$245M
|
–
|
–
|
–
|
|
|
2
|
Boxer Capital
San Diego,
California
|
$152M
|
–
|
–
|
–
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$110M
|
–
|
–
|
–
|
|
|
4
|
Canaan Partners XI
Menlo Park,
California
|
$104M
|
–
|
–
|
–
|
|
|
5
|
Nextech Invest
Zurich,
Switzerland
|
$95.4M
|
–
|
–
|
–
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$79.3M
|
+$550K
|
+26,187
|
+0.8%
|
|
|
7
|
TCG Crossover Management
Palo Alto,
California
|
$46.8M
|
–
|
–
|
–
|
|
|
8
|
|
$35.6M
|
+$2.04M
|
+97,317
|
+7%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$29.3M
|
+$145K
|
+6,907
|
+0.6%
|
|
|
10
|
Janus Henderson Group
London,
|
$25M
|
+$22.4M
|
+1,067,196
|
New
|
|
|
11
|
5AM Venture Management
San Francisco,
California
|
$22.1M
|
–
|
–
|
–
|
|
|
12
|
|
$18.1M
|
–
|
–
|
–
|
|
|
13
|
Frazier Life Sciences Management
Palo Alto,
California
|
$17.2M
|
-$2.12M
|
-101,200
|
-12%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$12.3M
|
+$10.8K
|
+516
|
+0.1%
|
|
|
15
|
Perceptive Advisors
New York
|
$12M
|
-$10.4M
|
-496,141
|
-49%
|
|
|
16
|
Kynam Capital Management
Princeton,
New Jersey
|
$11M
|
-$2.07M
|
-98,768
|
-17%
|
|
|
17
|
Sio Capital Management
New York
|
$9.42M
|
-$4.19M
|
-199,424
|
-33%
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$9.05M
|
+$341K
|
+16,248
|
+4%
|
|
|
19
|
|
$8.67M
|
+$81.8K
|
+3,896
|
+1%
|
|
|
20
|
Ally Bridge Group
New York
|
$6.35M
|
+$114K
|
+5,415
|
+2%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$5.04M
|
+$1.24M
|
+58,902
|
+38%
|
|
|
22
|
Adage Capital Partners
Boston,
Massachusetts
|
$4.7M
|
+$4.2M
|
+200,000
|
New
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$4.08M
|
+$79.6K
|
+3,792
|
+2%
|
|
|
24
|
Jennison Associates
New York
|
$3.72M
|
+$186K
|
+8,837
|
+6%
|
|
|
25
|
Tang Capital Management
San Diego,
California
|
$3.53M
|
+$2.26M
|
+107,777
|
+255%
|
|
