Vanguard Group
TYRA icon

Vanguard Group’s Tyra Biosciences TYRA Stock Holding History

Vanguard Group’s Portfolio TYRA Stock Details TYRA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		$41.3M Buy
1,572,785
+52,600
+3% +$966K ﹤0.01% 2272
2025
Q3 		$21.3M Buy
1,520,185
+118,492
+8% +$1.35M ﹤0.01% 2590
2025
Q2 		$13.4M Buy
1,401,693
+183,322
+15% +$1.74M ﹤0.01% 2750
2025
Q1 		$11.3M Buy
1,218,371
+10,606
+0.9% +$137K ﹤0.01% 2774
2024
Q4 		$16.8M Sell
1,207,765
-37,643
-3% -$683K ﹤0.01% 2669
2024
Q3 		$29.3M Buy
1,245,408
+6,907
+0.6% +$145K ﹤0.01% 2408
2024
Q2 		$19.8M Buy
1,238,501
+338,701
+38% +$5.83M ﹤0.01% 2574
2024
Q1 		$14.8M Buy
899,800
+140,833
+19% +$2.31M ﹤0.01% 2750
2023
Q4 		$10.5M Buy
758,967
+26,383
+4% +$342K ﹤0.01% 2918
2023
Q3 		$10.1M Buy
732,584
+83,709
+13% +$1.24M ﹤0.01% 2871
2023
Q2 		$11.1M Buy
648,875
+9,551
+1% +$139K ﹤0.01% 2888
2023
Q1 		$10.3M Buy
639,324
+34,957
+6% +$416K ﹤0.01% 2921
2022
Q4 		$4.59M Buy
604,367
+4,414
+0.7% +$31.2K ﹤0.01% 3343
2022
Q3 		$5.27M Buy
599,953
+8,844
+1% +$80.9K ﹤0.01% 3297
2022
Q2 		$4.23M Buy
591,109
+75,472
+15% +$601K ﹤0.01% 3465
2022
Q1 		$5.52M Sell
515,637
-846
-0.2% -$10K ﹤0.01% 3480
2021
Q4 		$7.27M Buy
+516,483
New +$10.3M ﹤0.01% 3408

Other funds holding TYRA

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
NI
Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return
APMC
Alta Partners Management Company Jackson, Wyoming $127M AUM 230.85% 1-Year Est. Return
CC
Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return
CPX
Canaan Partners XI Menlo Park, California $127M AUM 217.49% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return
VPC
Vestal Point Capital New York $3.58B AUM 189.12% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

Vanguard Group's TYRA Position: Q4 2025 in Review

Vanguard Group increased its Tyra Biosciences (TYRA) stake by 3.5% in Q4 2025, buying an estimated $966K and bringing the position to 1,572,785 shares worth $41.3M. The position accounts for ﹤0.01% of the portfolio, ranked #2272.

Vanguard Group first reported a position in TYRA in Q4 2021 and has held it in 17 quarters since. 133 funds tracked by Wall St. Rank hold TYRA as of Q4 2025.

  • Vanguard Group held 1,572,785 shares of Tyra Biosciences worth $41.3M as of Q4 2025.
  • Vanguard Group bought 52,600 Tyra Biosciences shares in Q4 2025, an estimated $966K.
  • Tyra Biosciences made up ﹤0.01% of Vanguard Group's portfolio in Q4 2025, its #2272 holding.
  • Vanguard Group first reported a position in Tyra Biosciences in Q4 2021 and has held it in 17 quarters since.
  • 133 funds tracked by Wall St. Rank held Tyra Biosciences as of Q4 2025.

Based on Vanguard Group's 13F filing for Q4 2025, filed 29 Jan 2026.