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Tyra Biosciences

113 hedge funds and large institutions have $676M invested in Tyra Biosciences in 2024 Q4 according to their latest regulatory filings, with 36 funds opening new positions, 34 increasing their positions, 25 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more first-time investments, than exits

New positions opened: 36 | Existing positions closed: 18

36% more repeat investments, than reductions

Existing positions increased: 34 | Existing positions reduced: 25

19% more funds holding

Funds holding: 95113 (+18)

6.97% more ownership

Funds ownership: 89.1%96.07% (+7%)

36% less call options, than puts

Call options by funds: $53K | Put options by funds: $83K

38% less funds holding in top 10

Funds holding in top 10: 85 (-3)

39% less capital invested

Capital invested by funds: $1.11B → $676M (-$430M)

Holders
113
Holders Change
+18
Holders Change %
+18.95%
% of All Funds
1.49%
Holding in Top 10
5
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-37.5%
% of All Funds
0.07%
New
36
Increased
34
Reduced
25
Closed
18
Calls
$53K
Puts
$83K
Net Calls
-$30K
Net Calls Change
-$8.3M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$148M +$4M +220,681 +2%
CPX
2
Canaan Partners XI
California
$58.1M -$4.18M -230,134 -5%
APMC
3
Alta Partners Management Company
Wyoming
$56.7M +$74M +4,080,296 New
NI
4
Nextech Invest
Switzerland
$56.4M
BI
5
BVF Inc
California
$54.8M -$13M -717,000 -15%
Fidelity Investments
6
Fidelity Investments
Massachusetts
$43.2M -$4.81M -264,880 -8%
BCM
7
Boxer Capital Management
California
$28.2M +$36.8M +2,027,678 New
TCM
8
TCG Crossover Management
California
$27.6M
Janus Henderson Group
9
Janus Henderson Group
United Kingdom
$24.3M +$12.3M +679,124 +64%
BlackRock
10
BlackRock
New York
$23.9M +$3.67M +202,332 +13%
O
11
OrbiMed
New York
$20.4M +$12.7M +701,448 +91%
Vanguard Group
12
Vanguard Group
Pennsylvania
$16.8M -$683K -37,643 -3%
FCM
13
Farallon Capital Management
California
$13.9M +$18.2M +1,000,981 New
VPC
14
Vestal Point Capital
New York
$13.8M +$18M +990,000 New
5VM
15
5AM Venture Management
California
$13.1M
KCM
16
Kynam Capital Management
New Jersey
$7.37M +$1.13M +62,531 +13%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$7.2M -$102K -5,612 -1%
State Street
18
State Street
Massachusetts
$5.67M +$415K +22,841 +6%
Pictet Asset Management
19
Pictet Asset Management
Switzerland
$4.92M +$6.42M +354,012 New
Millennium Management
20
Millennium Management
New York
$4.38M +$5.53M +304,637 +2,900%
Jacobs Levy Equity Management
21
Jacobs Levy Equity Management
New Jersey
$3.4M +$4.43M +244,245 New
SCM
22
Sio Capital Management
New York
$3.35M -$2.9M -160,000 -40%
Northern Trust
23
Northern Trust
Illinois
$3.1M +$153K +8,411 +4%
Adage Capital Partners
24
Adage Capital Partners
Massachusetts
$2.78M
ABG
25
Ally Bridge Group
New York
$2.43M -$1.72M -95,012 -35%

TYRA Hedge Fund Activity: Q4 2024 in Review

113 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Tyra Biosciences (TYRA) for Q4 2024, worth a combined $676M — down 39% from $1.11B a quarter earlier.

Buyers outnumbered sellers: 36 funds opened new TYRA positions and 18 closed out — a net gain of 18 holders — while 34 added to existing stakes and 25 trimmed.

The largest buyer was Farallon Capital Management, opening a new position worth an estimated $18.2M. The largest seller was Frazier Life Sciences Management, exiting entirely with an estimated $17.2M sold.

  • 113 institutional investors held Tyra Biosciences (TYRA) as of Q4 2024, up from 95 in Q3 2024.
  • Funds reported $676M of Tyra Biosciences stock for Q4 2024, down 39% quarter-over-quarter.
  • 36 funds opened new Tyra Biosciences positions in Q4 2024 and 18 closed out, a net change of +18 holders.
  • The largest Tyra Biosciences buyer in Q4 2024 was Farallon Capital Management, an estimated $18.2M added.
  • The largest Tyra Biosciences seller in Q4 2024 was Frazier Life Sciences Management, an estimated $17.2M sold.

Based on aggregated 13F filings for Q4 2024.