Janus Henderson Group
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Janus Henderson Group’s Tyra Biosciences TYRA Stock Holding History

Janus Henderson Group’s Portfolio TYRA Stock Details TYRA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$149M Buy
3,890,589
+955,147
+33% +$30.9M 0.07% 234
2025
Q4 		$77.1M Buy
2,935,442
+60,638
+2% +$1.11M 0.03% 335
2025
Q3 		$40.2M Buy
2,874,804
+18,514
+0.6% +$211K 0.02% 461
2025
Q2 		$27.3M Buy
2,856,290
+163,053
+6% +$1.55M 0.01% 505
2025
Q1 		$26.3M Buy
2,693,237
+946,917
+54% +$12.3M 0.01% 506
2024
Q4 		$24.3M Buy
1,746,320
+679,124
+64% +$12.3M 0.01% 535
2024
Q3 		$25M Buy
+1,067,196
New +$22.4M 0.01% 528
2022
Q4 		– Sell
-1,364,036
Closed -$12M – 2505
2022
Q3 		$12M Buy
1,364,036
+651,737
+91% +$5.96M ﹤0.01% 787
2022
Q2 		$5.09M Sell
712,299
-196,893
-22% -$1.57M ﹤0.01% 840
2022
Q1 		$9.72M Sell
909,192
-257,289
-22% -$3.05M ﹤0.01% 890
2021
Q4 		$15.9M Sell
1,166,481
-208,167
-15% -$4.14M 0.01% 835
2021
Q3 		$22.8M Buy
+1,374,648
New +$26.3M 0.01% 763

Other funds holding TYRA

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
NI
Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return
APMC
Alta Partners Management Company Jackson, Wyoming $151M AUM 296.21% 1-Year Est. Return
FCM
Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return
CC
Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $4.89B AUM 251.12% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return

Janus Henderson Group's TYRA Position: Q1 2026 in Review

Janus Henderson Group increased its Tyra Biosciences (TYRA) stake by 33% in Q1 2026, buying an estimated $30.9M and bringing the position to 3,890,589 shares worth $149M. The position accounts for 0.07% of the portfolio, ranked #234.

Janus Henderson Group first reported a position in TYRA in Q3 2021 and has held it in 12 quarters since. 164 funds tracked by Wall St. Rank hold TYRA as of Q1 2026.

  • Janus Henderson Group held 3,890,589 shares of Tyra Biosciences worth $149M as of Q1 2026.
  • Janus Henderson Group bought 955,147 Tyra Biosciences shares in Q1 2026, an estimated $30.9M.
  • Tyra Biosciences made up 0.07% of Janus Henderson Group's portfolio in Q1 2026, its #234 holding.
  • Janus Henderson Group first reported a position in Tyra Biosciences in Q3 2021 and has held it in 12 quarters since.
  • 164 funds tracked by Wall St. Rank held Tyra Biosciences as of Q1 2026.

Based on Janus Henderson Group's 13F filing for Q1 2026, filed 15 May 2026.