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Commodore Capital’s Tyra Biosciences TYRA Stock Holding History

Commodore Capital’s Portfolio TYRA Stock Details TYRA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$59.9M Sell
1,875,000
-600,000
-24% -$19.8M 3.57% 11
2026
Q1 		$94.8M Sell
2,475,000
-900,000
-27% -$29.1M 5.48% 6
2025
Q4 		$88.7M Hold
3,375,000
– – 5.91% 3
2025
Q3 		$47.2M Buy
3,375,000
+275,000
+9% +$3.14M 2.31% 17
2025
Q2 		$29.7M Buy
3,100,000
+2,150,000
+226% +$20.4M 2.09% 20
2025
Q1 		$8.84M Buy
+950,000
New +$12.3M 0.65% 27

Other funds holding TYRA

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM
APMC
Alta Partners Management Company Jackson, Wyoming $127M AUM 230.85% 1-Year Est. Return
NI
Nextech Invest Zurich, Switzerland $2.11B AUM 413.84% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $4.16B AUM 983.43% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $5.34B AUM 380.18% 1-Year Est. Return

Commodore Capital's TYRA Position: Q2 2026 in Review

Commodore Capital reduced its Tyra Biosciences (TYRA) stake by 24% in Q2 2026, selling an estimated $19.8M and leaving 1,875,000 shares worth $59.9M. The position accounts for 3.57% of the portfolio, ranked #11.

Commodore Capital first reported a position in TYRA in Q1 2025 and has held it in 6 quarters since. The position peaked at $94.8M in Q1 2026. 169 funds tracked by Wall St. Rank hold TYRA as of Q2 2026.

  • Commodore Capital held 1,875,000 shares of Tyra Biosciences worth $59.9M as of Q2 2026.
  • Commodore Capital sold 600,000 Tyra Biosciences shares in Q2 2026, an estimated $19.8M.
  • Tyra Biosciences made up 3.57% of Commodore Capital's portfolio in Q2 2026, its #11 holding.
  • Commodore Capital first reported a position in Tyra Biosciences in Q1 2025 and has held it in 6 quarters since.
  • Commodore Capital's Tyra Biosciences position peaked at $94.8M in Q1 2026.
  • 169 funds tracked by Wall St. Rank held Tyra Biosciences as of Q2 2026.

Based on Commodore Capital's 13F filing for Q2 2026, filed 14 Aug 2026.