5AM Venture Management’s Tyra Biosciences TYRA Stock Holding History

5AM Venture Management’s Portfolio TYRA Stock Details TYRA Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$39.4M	Hold	1,029,298	–	–	10.94%	3
2025 Q4	$27.1M	Buy	1,029,298 +90,000	+10%	+$1.65M	8.51%	3
2025 Q3	$13.1M	Hold	939,298	–	–	4.81%	10
2025 Q2	$8.99M	Hold	939,298	–	–	3.46%	13
2025 Q1	$8.74M	Hold	939,298	–	–	3.3%	13
2024 Q4	$13.1M	Hold	939,298	–	–	3.12%	15
2024 Q3	$22.1M	Hold	939,298	–	–	4.56%	7
2024 Q2	$15M	Hold	939,298	–	–	3.36%	7
2024 Q1	$15.4M	Buy	939,298 +384,319	+69%	+$6.3M	3.45%	11
2023 Q4	$7.69M	Buy	554,979 +143,529	+35%	+$1.86M	2.04%	15
2023 Q3	$5.67M	Buy	+411,450	New	+$6.1M	1.63%	19

Other funds holding TYRA

RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return

Fidelity Investments

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return

Janus Henderson Group

Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return

Alta Partners Management Company Jackson, Wyoming $151M AUM 296.21% 1-Year Est. Return

Farallon Capital Management San Francisco, California $15.3B AUM 50.95% 1-Year Est. Return

TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return

Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return

BlackRock New York $5.7T AUM 30.48% 1-Year Est. Return

Paradigm Biocapital Advisors New York $4.89B AUM 251.12% 1-Year Est. Return