Barclays
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Barclays’s Tyra Biosciences TYRA Stock Holding History

Barclays’s Portfolio TYRA Stock Details TYRA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$31.9M Buy
833,399
+757,090
+992% +$24.5M 0.01% 903
2025
Q4 		$2.01M Buy
76,309
+19,183
+34% +$352K ﹤0.01% 2931
2025
Q3 		$799K Sell
57,126
-4,429
-7% -$50.5K ﹤0.01% 3508
2025
Q2 		$589K Buy
61,555
+19,044
+45% +$181K ﹤0.01% 3666
2025
Q1 		$395K Sell
42,511
-559
-1% -$7.23K ﹤0.01% 3669
2024
Q4 		$599K Buy
43,070
+5,445
+14% +$98.8K ﹤0.01% 3713
2024
Q3 		$885K Buy
37,625
+25,106
+201% +$527K ﹤0.01% 3436
2024
Q2 		$200K Buy
12,519
+2,669
+27% +$45.9K ﹤0.01% 3580
2024
Q1 		$162K Sell
9,850
-9,377
-49% -$154K ﹤0.01% 4227
2023
Q4 		$266K Buy
19,227
+16,721
+667% +$216K ﹤0.01% 4285
2023
Q3 		$34.5K Sell
2,506
-282
-10% -$4.18K ﹤0.01% 4014
2023
Q2 		$47.5K Sell
2,788
-3,997
-59% -$58K ﹤0.01% 3857
2023
Q1 		$109K Buy
6,785
+3,204
+89% +$38.1K ﹤0.01% 4125
2022
Q4 		$27.2K Buy
3,581
+3,025
+544% +$21.4K ﹤0.01% 4747
2022
Q3 		$5K Sell
556
-102
-16% -$933 ﹤0.01% 4510
2022
Q2 		$5K Sell
658
-1,257
-66% -$10K ﹤0.01% 4791
2022
Q1 		$20K Buy
+1,915
New +$22.7K ﹤0.01% 4450

Other funds holding TYRA

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
NI
Nextech Invest Zurich, Switzerland $1.42B AUM 304.47% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
APMC
Alta Partners Management Company Jackson, Wyoming $151M AUM 296.21% 1-Year Est. Return
FCM
Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return
CC
Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $4.89B AUM 251.12% 1-Year Est. Return

Barclays's TYRA Position: Q1 2026 in Review

Barclays increased its Tyra Biosciences (TYRA) stake by 992% in Q1 2026, buying an estimated $24.5M and bringing the position to 833,399 shares worth $31.9M. The position accounts for 0.01% of the portfolio, ranked #903.

Barclays first reported a position in TYRA in Q1 2022 and has held it in 17 quarters since. 164 funds tracked by Wall St. Rank hold TYRA as of Q1 2026.

  • Barclays held 833,399 shares of Tyra Biosciences worth $31.9M as of Q1 2026.
  • Barclays bought 757,090 Tyra Biosciences shares in Q1 2026, an estimated $24.5M.
  • Tyra Biosciences made up 0.01% of Barclays's portfolio in Q1 2026, its #903 holding.
  • Barclays first reported a position in Tyra Biosciences in Q1 2022 and has held it in 17 quarters since.
  • 164 funds tracked by Wall St. Rank held Tyra Biosciences as of Q1 2026.

Based on Barclays's 13F filing for Q1 2026, filed 15 May 2026.