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Tyra Biosciences
TYRA

Overview Fund Activity

121 hedge funds and large institutions have $542M invested in Tyra Biosciences in 2025 Q2 according to their latest regulatory filings, with 18 funds opening new positions, 61 increasing their positions, 21 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
121
Holders Change
+4
Holders Change %
+3.42%
% of All Funds
1.62%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
18
Increased
61
Reduced
21
Closed
14
Calls
$1K
Puts
–
Net Calls
+$1K
Net Calls Change
-$182K

Top Buyers

1
CC
Commodore Capital
New York
$29.7M
2
RCM
RA Capital Management
Massachusetts
$117M
3
SCM
Sio Capital Management
New York
$7.75M
4
Balyasny Asset Management
Balyasny Asset Management
Illinois
$5.58M
5
Bank of America
Bank of America
North Carolina
$3.57M

Top Sellers

1
Fidelity Investments
Fidelity Investments
Massachusetts
$117K
2
O
OrbiMed
New York
$7.7M
3
CPX
Canaan Partners XI
California
$34.5M
4
Pictet Asset Management
Pictet Asset Management
Switzerland
$0
5
VPC
Vestal Point Capital
New York
$25.4M
Name Holding Trade Value Shares
Change 		Shares
Change %
Point72 Asset Management
26
Point72 Asset Management
Connecticut
$2.15M +$1.68M +175,100 +353%
Citadel Advisors
27
Citadel Advisors
Florida
$2.07M +$1.15M +119,854 +124%
Northern Trust
28
Northern Trust
Illinois
$1.96M -$107K -11,139 -5%
CP
29
Caligan Partners
New York
$1.82M +$1.58M +164,950 +660%
Charles Schwab
30
Charles Schwab
California
$1.7M +$134K +13,996 +9%
Renaissance Technologies
31
Renaissance Technologies
New York
$1.29M +$801K +83,700 +163%
Axa
32
Axa
France
$1.23M +$2.02K +211 +0.2%
CSS
33
Cubist Systematic Strategies
Connecticut
$1.17M +$289K +30,192 +33%
Two Sigma Investments
34
Two Sigma Investments
New York
$1.01M +$392K +41,007 +63%
Goldman Sachs
35
Goldman Sachs
New York
$1.01M +$264K +27,589 +35%
Wellington Management Group
36
Wellington Management Group
Massachusetts
$986K -$9.66K -1,009 -1%
JPMorgan Chase & Co
37
JPMorgan Chase & Co
New York
$985K +$167K +17,427 +20%
WP
38
Woodline Partners
California
$958K – – –
BNP Paribas Financial Markets
39
BNP Paribas Financial Markets
France
$935K +$275K +28,786 +42%
Two Sigma Advisers
40
Two Sigma Advisers
New York
$833K +$353K +36,900 +74%
ICCON
41
Investment Counsel Company of Nevada
Nevada
$814K – – –
Ameriprise
42
Ameriprise
Minnesota
$771K +$771K +80,602 New
NL
43
Nuveen LLC
North Carolina
$770K +$291K +30,443 +61%
State of Wisconsin Investment Board
44
State of Wisconsin Investment Board
Wisconsin
$732K +$170K +17,737 +30%
OC
45
Oppenheimer & Co
New York
$708K -$7.39K -772 -1%
A
46
AlphaQuest
New York
$699K +$416K +43,451 +147%
JF
47
Jump Financial
Illinois
$681K +$413K +43,170 +154%
ECM
48
ExodusPoint Capital Management
New York
$645K +$356K +37,207 +123%
Raymond James Financial
49
Raymond James Financial
Florida
$605K +$84.6K +8,843 +16%
Barclays
50
Barclays
United Kingdom
$589K +$182K +19,044 +45%
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