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Praxis Precision Medicines
PRAX

Overview Fund Activity

141 hedge funds and large institutions have $1.01B invested in Praxis Precision Medicines in 2025 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 64 increasing their positions, 34 reducing their positions, and 32 closing their positions.

Holders
141
Holders Change
-8
Holders Change %
-5.37%
% of All Funds
1.89%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
25
Increased
64
Reduced
34
Closed
32
Calls
$21.9M
Puts
$11.2M
Net Calls
+$10.7M
Net Calls Change
+$15.7M

Top Buyers

1
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$107M
2
Point72 Asset Management
2
Point72 Asset Management
Connecticut
$40.1M
3
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$61.9M
4
BBA
4
Baker Bros. Advisors
New York
$29M
5
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$83M

Top Sellers

1
VA
1
VR Adviser
New York
$0
2
Capital Research Global Investors
2
Capital Research Global Investors
California
$0
3
PA
3
Perceptive Advisors
New York
$31.7M
4
SCM
4
Soleus Capital Management
Connecticut
$40.7M
5
SCM
5
Silverarc Capital Management
Massachusetts
$421K
Name Market Value Shares Shares
Change 		Shares
Change %
AQR Capital Management
76
AQR Capital Management
Connecticut
$613K 14,580 +14,580 New
JPMorgan Chase & Co
77
JPMorgan Chase & Co
New York
$586K 13,938 +2,459 +21%
Jane Street
78
Jane Street
New York
$547K 13,003 +3,514 +37%
Deutsche Bank
79
Deutsche Bank
Germany
$510K 12,124 -1,737 -13%
GCP
80
GSA Capital Partners
United Kingdom
$505K 12,008 -969 -7%
Citigroup
81
Citigroup
New York
$499K 11,866 -33,766 -74%
Wells Fargo
82
Wells Fargo
California
$473K 11,252 +2,735 +32%
AA
83
ALPS Advisors
Colorado
$462K 10,994 -3,944 -26%
MIM
84
MetLife Investment Management
New Jersey
$442K 10,520 -77 -0.7%
HSA
85
Hussman Strategic Advisors
Maryland
$442K 10,500 – –
Citadel Advisors
86
Citadel Advisors
Florida
$436K 10,366 -51,844 -83%
SCM
87
Silverarc Capital Management
Massachusetts
$421K 10,000 -156,074 -94%
IIM
88
INTECH Investment Management
Florida
$367K 8,719 -79 -0.9%
BHCM
89
Brevan Howard Capital Management
Jersey
$358K 8,503 +8,503 New
New York State Common Retirement Fund
90
New York State Common Retirement Fund
New York
$278K 6,600 – –
Two Sigma Investments
91
Two Sigma Investments
New York
$274K 6,509 -12,299 -65%
Creative Planning
92
Creative Planning
Kansas
$273K 6,495 +6,495 New
State Board of Administration of Florida Retirement System
93
State Board of Administration of Florida Retirement System
Florida
$270K 6,425 +385 +6%
SPS
94
Susquehanna Portfolio Strategies
Pennsylvania
$242K 5,750 +5,750 New
Cerity Partners
95
Cerity Partners
New York
$236K 5,611 +5,611 New
PA
96
Profund Advisors
Maryland
$221K 5,261 -847 -14%
VF
97
Virtu Financial
New York
$213K 5,058 +5,058 New
Norges Bank
98
Norges Bank
Norway
$210K 5,000 +5,000 New
JFG
99
Jefferies Financial Group
New York
$210K 5,000 +5,000 New
MS
100
Maven Securities
Jersey
$210K 5,000 +5,000 New
2 3
4
5 6