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Praxis Precision Medicines
PRAX

Overview Fund Activity

141 hedge funds and large institutions have $1.01B invested in Praxis Precision Medicines in 2025 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 64 increasing their positions, 34 reducing their positions, and 32 closing their positions.

Holders
141
Holders Change
-8
Holders Change %
-5.37%
% of All Funds
1.89%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
25
Increased
64
Reduced
34
Closed
32
Calls
$21.9M
Puts
$11.2M
Net Calls
+$10.7M
Net Calls Change
+$15.7M

Top Buyers

1
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$107M
2
Point72 Asset Management
2
Point72 Asset Management
Connecticut
$40.1M
3
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$61.9M
4
BBA
4
Baker Bros. Advisors
New York
$29M
5
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$83M

Top Sellers

1
VA
1
VR Adviser
New York
$0
2
Capital Research Global Investors
2
Capital Research Global Investors
California
$0
3
PA
3
Perceptive Advisors
New York
$31.7M
4
SCM
4
Soleus Capital Management
Connecticut
$40.7M
5
SCM
5
Silverarc Capital Management
Massachusetts
$421K
Name Market Value Shares Shares
Change 		Shares
Change %
TLP
26
Tri Locum Partners
New York
$8.22M 195,432 +111,773 +134%
5VM
27
5AM Venture Management
California
$7.15M 170,000 – –
VC
28
Vivo Capital
California
$7.05M 167,600 +167,600 New
Charles Schwab
29
Charles Schwab
California
$6.41M 152,444 +11,364 +8%
VCIM
30
Velan Capital Investment Management
Georgia
$6.28M 149,334 -35,666 -19%
Alyeska Investment Group
31
Alyeska Investment Group
Illinois
$5.26M 125,000 -25,000 -17%
Verition Fund Management
32
Verition Fund Management
Connecticut
$4.98M 118,482 -81,175 -41%
BFM
33
Boothbay Fund Management
New York
$4.97M 118,121 +71,495 +153%
SFM
34
Sphera Funds Management
Israel
$4.62M 109,757 -30,903 -22%
SSA
35
Schonfeld Strategic Advisors
New York
$4.23M 100,702 +94,628 +1,558%
UBS AM
36
UBS AM
Illinois
$4.08M 96,945 +9,864 +11%
Barclays
37
Barclays
United Kingdom
$3.73M 88,724 +56,956 +179%
UBS Group
38
UBS Group
Switzerland
$3.64M 86,534 -106,375 -55%
PHS
39
PFM Health Sciences
California
$3.56M 84,713 -76,153 -47%
ABG
40
Ally Bridge Group
New York
$3.4M 80,880 -14,702 -15%
Pictet Asset Management
41
Pictet Asset Management
Switzerland
$3.33M 79,143 +555 +0.7%
ACP
42
Acuta Capital Partners
California
$3.12M 74,087 -13,054 -15%
KCM
43
Kennedy Capital Management
Missouri
$2.96M 70,445 +5,180 +8%
HS
44
HighVista Strategies
Massachusetts
$2.83M 67,288 +28,002 +71%
7IH
45
72 Investment Holdings
Connecticut
$2.77M 65,933 – –
TD Asset Management
46
TD Asset Management
Ontario, Canada
$2.69M 63,938 +26,800 +72%
CS
47
Candriam SCA
Luxembourg
$2.68M 63,671 – –
EAM
48
Exome Asset Management
New York
$2.48M 59,002 +59,002 New
Manulife (Manufacturers Life Insurance)
49
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.36M 56,131 +23,639 +73%
Wellington Management Group
50
Wellington Management Group
Massachusetts
$2.35M 55,881 +5,105 +10%
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