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Praxis Precision Medicines
PRAX

Overview Fund Activity

141 hedge funds and large institutions have $1.01B invested in Praxis Precision Medicines in 2025 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 64 increasing their positions, 34 reducing their positions, and 32 closing their positions.

Holders
141
Holders Change
-8
Holders Change %
-5.37%
% of All Funds
1.89%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
25
Increased
64
Reduced
34
Closed
32
Calls
$21.9M
Puts
$11.2M
Net Calls
+$10.7M
Net Calls Change
+$15.7M

Top Buyers

1
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$107M
2
Point72 Asset Management
2
Point72 Asset Management
Connecticut
$40.1M
3
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$61.9M
4
BBA
4
Baker Bros. Advisors
New York
$29M
5
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$83M

Top Sellers

1
VA
1
VR Adviser
New York
$0
2
Capital Research Global Investors
2
Capital Research Global Investors
California
$0
3
PA
3
Perceptive Advisors
New York
$31.7M
4
SCM
4
Soleus Capital Management
Connecticut
$40.7M
5
SCM
5
Silverarc Capital Management
Massachusetts
$421K
Name Market Value Shares Shares
Change 		Shares
Change %
Bank of New York Mellon
51
Bank of New York Mellon
New York
$2.21M 52,553 +6,246 +13%
WP
52
Woodline Partners
California
$1.93M 45,952 -129,775 -74%
Jacobs Levy Equity Management
53
Jacobs Levy Equity Management
New Jersey
$1.9M 45,082 +5,083 +13%
CM
54
Caption Management
Oklahoma
$1.64M 39,036 +20,756 +114%
NL
55
Nuveen LLC
North Carolina
$1.62M 38,549 +23,787 +161%
Fidelity Investments
56
Fidelity Investments
Massachusetts
$1.6M 38,100 +2,381 +7%
BGI
57
B Group Inc
Texas
$1.47M 35,000 +16,000 +84%
SC
58
Stempoint Capital
New York
$1.36M 32,255 +32,255 New
Swiss National Bank
59
Swiss National Bank
Switzerland
$1.3M 30,800 +3,700 +14%
AG
60
Algert Global
California
$1.16M 27,570 +6,080 +28%
RhumbLine Advisers
61
RhumbLine Advisers
Massachusetts
$1.15M 27,341 +3,047 +13%
Simplex Trading
62
Simplex Trading
Illinois
$1.07M 25,328 +22,030 +668%
Rafferty Asset Management
63
Rafferty Asset Management
New York
$1.04M 24,805 -4,440 -15%
Capital Fund Management (CFM)
64
Capital Fund Management (CFM)
France
$1.02M 24,292 +24,292 New
Mirae Asset Global ETFs Holdings
65
Mirae Asset Global ETFs Holdings
Hong Kong
$1.01M 23,873 +12,165 +104%
Royal Bank of Canada
66
Royal Bank of Canada
Ontario, Canada
$950K 22,593 +22,485 +20,819%
UOC
67
UBS O'Connor
Illinois
$921K 21,892 -4,901 -18%
PCM
68
Prelude Capital Management
New York
$837K 19,900 +19,900 New
D.E. Shaw & Co
69
D.E. Shaw & Co
New York
$801K 19,056 +6,848 +56%
AllianceBernstein
70
AllianceBernstein
Tennessee
$759K 18,040 -33,076 -65%
Legal & General Group
71
Legal & General Group
United Kingdom
$701K 16,670 +2,261 +16%
California State Teachers Retirement System (CalSTRS)
72
California State Teachers Retirement System (CalSTRS)
California
$687K 16,346 – –
Invesco
73
Invesco
Georgia
$670K 15,939 +4,261 +36%
SI
74
Sofinnova Investments
California
$661K 15,717 -141,923 -90%
State of Wisconsin Investment Board
75
State of Wisconsin Investment Board
Wisconsin
$621K 14,759 +148 +1%
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3
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