First Trust Advisors
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First Trust Advisors’s Praxis Precision Medicines PRAX Stock Holding History

First Trust Advisors’s Portfolio PRAX Stock Details PRAX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$5.39M Sell
16,087
-17,248
-52% -$5.46M ﹤0.01% 1538
2026
Q1 		$10.7M Sell
33,335
-55,369
-62% -$17.1M 0.01% 1069
2025
Q4 		$26.1M Buy
88,704
+59,738
+206% +$11.1M 0.02% 799
2025
Q3 		$1.54M Buy
+28,966
New +$1.4M ﹤0.01% 1949

Other funds holding PRAX

JT
Jupiter Topco New York $245B AUM
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return
OAG
Orbis Allan Gray Hamilton, Bermuda $29.1B AUM 60.8% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $71.3B AUM 56.8% 1-Year Est. Return

First Trust Advisors's PRAX Position: Q2 2026 in Review

First Trust Advisors reduced its Praxis Precision Medicines (PRAX) stake by 52% in Q2 2026, selling an estimated $5.46M and leaving 16,087 shares worth $5.39M. The position accounts for ﹤0.01% of the portfolio, ranked #1538.

First Trust Advisors first reported a position in PRAX in Q3 2025 and has held it in 4 quarters since. The position peaked at $26.1M in Q4 2025. 310 funds tracked by Wall St. Rank hold PRAX as of Q2 2026.

  • First Trust Advisors held 16,087 shares of Praxis Precision Medicines worth $5.39M as of Q2 2026.
  • First Trust Advisors sold 17,248 Praxis Precision Medicines shares in Q2 2026, an estimated $5.46M.
  • Praxis Precision Medicines made up ﹤0.01% of First Trust Advisors's portfolio in Q2 2026, its #1538 holding.
  • First Trust Advisors first reported a position in Praxis Precision Medicines in Q3 2025 and has held it in 4 quarters since.
  • First Trust Advisors's Praxis Precision Medicines position peaked at $26.1M in Q4 2025.
  • 310 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q2 2026.

Based on First Trust Advisors's 13F filing for Q2 2026, filed 11 Aug 2026.