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Praxis Precision Medicines

162 hedge funds and large institutions have $1.67B invested in Praxis Precision Medicines in 2024 Q4 according to their latest regulatory filings, with 38 funds opening new positions, 56 increasing their positions, 52 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

280% more first-time investments, than exits

New positions opened: 38 | Existing positions closed: 10

155% more call options, than puts

Call options by funds: $74.7M | Put options by funds: $29.3M

53% more capital invested

Capital invested by funds: $1.09B → $1.67B (+$580M)

40% more funds holding in top 10

Funds holding in top 10: 57 (+2)

21% more funds holding

Funds holding: 134162 (+28)

10.29% more ownership

Funds ownership: 106.24%116.53% (+10%)

8% more repeat investments, than reductions

Existing positions increased: 56 | Existing positions reduced: 52

Holders
162
Holders Change
+28
Holders Change %
+20.9%
% of All Funds
2.13%
Holding in Top 10
7
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+40%
% of All Funds
0.09%
New
38
Increased
56
Reduced
52
Closed
10
Calls
$74.7M
Puts
$29.3M
Net Calls
+$45.5M
Net Calls Change
+$41.4M
Name Holding Trade Value Shares
Change
Change in
Stake
TD Asset Management
51
TD Asset Management
Ontario, Canada
$4.07M +$651K +9,000 +21%
D.E. Shaw & Co
52
D.E. Shaw & Co
New York
$3.69M +$118K +1,629 +4%
Bank of New York Mellon
53
Bank of New York Mellon
New York
$3.61M -$97.8K -1,351 -3%
FTM
54
First Turn Management
California
$3.5M +$3.29M +45,536 New
Pictet Asset Management
55
Pictet Asset Management
Switzerland
$3.5M +$3.29M +45,427 New
ABG
56
Ally Bridge Group
New York
$3.46M -$2.04M -28,203 -39%
SSA
57
Schonfeld Strategic Advisors
New York
$3.32M +$1.06M +14,649 +51%
SAM
58
Simplify Asset Management
Nevada
$3.32M +$3.12M +43,085 New
Jacobs Levy Equity Management
59
Jacobs Levy Equity Management
New Jersey
$3.08M
Manulife (Manufacturers Life Insurance)
60
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.96M +$242K +3,344 +10%
Barclays
61
Barclays
United Kingdom
$2.87M +$11.4K +158 +0.4%
TLP
62
Tri Locum Partners
New York
$2.87M +$2.7M +37,269 New
Jane Street
63
Jane Street
New York
$2.86M -$101K -1,401 -4%
Rafferty Asset Management
64
Rafferty Asset Management
New York
$2.59M -$125K -1,730 -5%
Qube Research & Technologies (QRT)
65
Qube Research & Technologies (QRT)
United Kingdom
$2.46M -$919K -12,704 -28%
MAP
66
Moody Aldrich Partners
Massachusetts
$2.36M -$67.1K -928 -3%
Ensign Peak Advisors
67
Ensign Peak Advisors
Utah
$2.13M +$2M +27,650 New
UOC
68
UBS O'Connor
Illinois
$2.04M -$867K -11,987 -31%
Swiss National Bank
69
Swiss National Bank
Switzerland
$2.01M +$72.4K +1,000 +4%
RhumbLine Advisers
70
RhumbLine Advisers
Massachusetts
$1.75M -$25.1K -347 -2%
Two Sigma Investments
71
Two Sigma Investments
New York
$1.54M -$195K -2,700 -12%
UBS AM
72
UBS AM
Illinois
$1.43M +$199K +2,747 +17%
PWA
73
PCG Wealth Advisors
Kansas
$1.33M -$5.57K -77 -0.4%
Simplex Trading
74
Simplex Trading
Illinois
$1.3M +$321K +4,436 +36%
American Century Companies
75
American Century Companies
Missouri
$1.2M +$382K +5,281 +51%

PRAX Hedge Fund Activity: Q4 2024 in Review

162 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Praxis Precision Medicines (PRAX) for Q4 2024, worth a combined $1.67B — up 53% from $1.09B a quarter earlier.

Buyers outnumbered sellers: 38 funds opened new PRAX positions and 10 closed out — a net gain of 28 holders — while 56 added to existing stakes and 52 trimmed.

The largest buyer was Morgan Stanley, adding an estimated $78.4M. The largest seller was Point72 Asset Management, cutting an estimated $37M.

  • 162 institutional investors held Praxis Precision Medicines (PRAX) as of Q4 2024, up from 134 in Q3 2024.
  • Funds reported $1.67B of Praxis Precision Medicines stock for Q4 2024, up 53% quarter-over-quarter.
  • 38 funds opened new Praxis Precision Medicines positions in Q4 2024 and 10 closed out, a net change of +28 holders.
  • The largest Praxis Precision Medicines buyer in Q4 2024 was Morgan Stanley, an estimated $78.4M added.
  • The largest Praxis Precision Medicines seller in Q4 2024 was Point72 Asset Management, an estimated $37M sold.

Based on aggregated 13F filings for Q4 2024.