5VM
PRAX icon

5AM Venture Management’s Praxis Precision Medicines PRAX Stock Holding History

5AM Venture Management’s Portfolio PRAX Stock Details PRAX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-170,000
Closed -$9.01M – 26
2025
Q3 		$9.01M Hold
170,000
– – 3.3% 13
2025
Q2 		$7.15M Hold
170,000
– – 2.75% 14
2025
Q1 		$6.44M Hold
170,000
– – 2.43% 17
2024
Q4 		$13.1M Sell
170,000
-170,000
-50% -$12.3M 3.12% 14
2024
Q3 		$19.6M Hold
340,000
– – 4.04% 10
2024
Q2 		$14.1M Hold
340,000
– – 3.15% 9
2024
Q1 		$20.7M Buy
+340,000
New +$15.3M 4.65% 6

Other funds holding PRAX

Janus Henderson Group
Janus Henderson Group London $209B AUM 37.72% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
OAG
Orbis Allan Gray Hamilton, Bermuda $29.1B AUM 60.8% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $71.3B AUM 56.8% 1-Year Est. Return
CAM
Cormorant Asset Management Boston, Massachusetts $1.95B AUM 773.9% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return

5AM Venture Management's PRAX Position: Q4 2025 in Review

5AM Venture Management sold out of Praxis Precision Medicines (PRAX) in Q4 2025, closing a stake of 170,000 shares — an estimated $9.01M sold.

5AM Venture Management first reported a position in PRAX in Q1 2024 and held it in 7 quarters. The position peaked at $20.7M in Q1 2024. 250 funds tracked by Wall St. Rank hold PRAX as of Q4 2025.

  • 5AM Venture Management reported no remaining Praxis Precision Medicines position as of Q4 2025 after selling out during the quarter.
  • 5AM Venture Management sold 170,000 Praxis Precision Medicines shares in Q4 2025, an estimated $9.01M.
  • 5AM Venture Management first reported a position in Praxis Precision Medicines in Q1 2024 and held it in 7 quarters.
  • 5AM Venture Management's Praxis Precision Medicines position peaked at $20.7M in Q1 2024.
  • 250 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q4 2025.

Based on 5AM Venture Management's 13F filing for Q4 2025, filed 17 Feb 2026.