Vanguard Group
PRAX icon

Vanguard Group’s Praxis Precision Medicines PRAX Stock Holding History

Vanguard Group’s Portfolio PRAX Stock Details PRAX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		$431M Buy
1,460,933
+193,647
+15% +$36.1M 0.01% 1146
2025
Q3 		$67.2M Buy
1,267,286
+51,642
+4% +$2.5M ﹤0.01% 2023
2025
Q2 		$51.1M Buy
1,215,644
+128,624
+12% +$4.9M ﹤0.01% 2106
2025
Q1 		$41.2M Buy
1,087,020
+23,381
+2% +$1.46M ﹤0.01% 2172
2024
Q4 		$81.9M Buy
1,063,639
+24,645
+2% +$1.78M ﹤0.01% 1950
2024
Q3 		$59.8M Buy
1,038,994
+61,849
+6% +$3.34M ﹤0.01% 2102
2024
Q2 		$40.4M Buy
977,145
+233,076
+31% +$11M ﹤0.01% 2230
2024
Q1 		$45.4M Buy
744,069
+373,131
+101% +$16.7M ﹤0.01% 2216
2023
Q4 		$8.26M Sell
370,938
-3
-0% -$54 ﹤0.01% 3059
2023
Q3 		$9.51M Buy
370,941
+213,303
+135% +$4.04M ﹤0.01% 2917
2023
Q2 		$2.72M Buy
157,638
+14,978
+10% +$229K ﹤0.01% 3565
2023
Q1 		$1.73M Buy
142,660
+23,574
+20% +$995K ﹤0.01% 3728
2022
Q4 		$4.25M Sell
119,086
-1,204
-1% -$37.5K ﹤0.01% 3384
2022
Q3 		$4.1M Sell
120,290
-49,130
-29% -$2.45M ﹤0.01% 3419
2022
Q2 		$6.23M Sell
169,420
-52,056
-24% -$5.56M ﹤0.01% 3251
2022
Q1 		$33.9M Buy
221,476
+1,980
+0.9% +$407K ﹤0.01% 2508
2021
Q4 		$64.9M Buy
219,496
+5,634
+3% +$1.65M ﹤0.01% 2209
2021
Q3 		$59.3M Buy
213,862
+44,012
+26% +$11.9M ﹤0.01% 2269
2021
Q2 		$46.6M Buy
169,850
+102,145
+151% +$36.6M ﹤0.01% 2415
2021
Q1 		$33.3M Buy
67,705
+2,164
+3% +$1.54M ﹤0.01% 2529
2020
Q4 		$54.1M Buy
+65,541
New +$38.3M ﹤0.01% 2156

Other funds holding PRAX

Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
OAG
Orbis Allan Gray Hamilton, Bermuda $23.7B AUM 65.43% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return
CAM
Cormorant Asset Management Boston, Massachusetts $1.99B AUM 737.95% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
DM
Deerfield Management New York $8.48B AUM 99.04% 1-Year Est. Return

Vanguard Group's PRAX Position: Q4 2025 in Review

Vanguard Group increased its Praxis Precision Medicines (PRAX) stake by 15% in Q4 2025, buying an estimated $36.1M and bringing the position to 1,460,933 shares worth $431M. The position accounts for 0.01% of the portfolio, ranked #1146.

Vanguard Group first reported a position in PRAX in Q4 2020 and has held it in 21 quarters since. 250 funds tracked by Wall St. Rank hold PRAX as of Q4 2025.

  • Vanguard Group held 1,460,933 shares of Praxis Precision Medicines worth $431M as of Q4 2025.
  • Vanguard Group bought 193,647 Praxis Precision Medicines shares in Q4 2025, an estimated $36.1M.
  • Praxis Precision Medicines made up 0.01% of Vanguard Group's portfolio in Q4 2025, its #1146 holding.
  • Vanguard Group first reported a position in Praxis Precision Medicines in Q4 2020 and has held it in 21 quarters since.
  • 250 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q4 2025.

Based on Vanguard Group's 13F filing for Q4 2025, filed 29 Jan 2026.