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Praxis Precision Medicines
PRAX

95 hedge funds and large institutions have $106M invested in Praxis Precision Medicines in 2022 Q2 according to their latest regulatory filings, with 21 funds opening new positions, 37 increasing their positions, 20 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

764% more call options, than puts

Call options by funds: $1.22M | Put options by funds: $141K

85% more repeat investments, than reductions

Existing positions increased: 37 | Existing positions reduced: 20

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

0.33% less ownership

Funds ownership: 6.65% → 6.32% (-0.33%)

8% less funds holding

Funds holding: 103 → 95 (-8)

22% less first-time investments, than exits

New positions opened: 21 | Existing positions closed: 27

77% less capital invested

Capital invested by funds: $463M → $106M (-$358M)

Holders
95
Holders Change
-8
Holders Change %
-7.77%
% of All Funds
1.6%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
21
Increased
37
Reduced
20
Closed
27
Calls
$1.22M
Puts
$141K
Net Calls
+$1.08M
Net Calls Change
-$897K

Top Buyers

1
State Street
State Street
Massachusetts
+$26.4M
2
PHS
PFM Health Sciences
California
+$17.3M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$6.86M
4
Acadian Asset Management
Acadian Asset Management
Massachusetts
+$5.9M
5
KCM
Kingdon Capital Management
New York
+$5.28M

Top Sellers

1
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$34M
2
Fidelity Investments
Fidelity Investments
Massachusetts
-$29.3M
3
ACA
Avoro Capital Advisors
New York
-$22M
4
AllianceBernstein
AllianceBernstein
Tennessee
-$14.2M
5
Point72 Asset Management
Point72 Asset Management
Connecticut
-$8.74M
Name Holding Trade Value Shares
Change 		Change in
Stake
Charles Schwab
26
Charles Schwab
California
$633K +$29.5K +276 +2%
Citigroup
27
Citigroup
New York
$597K +$1.52M +14,219 +704%
N
28
Nuveen
North Carolina
$591K +$117K +1,092 +7%
Rafferty Asset Management
29
Rafferty Asset Management
New York
$563K +$1.14M +10,643 +227%
Two Sigma Advisers
30
Two Sigma Advisers
New York
$541K +$1.16M +10,913 +286%
Renaissance Technologies
31
Renaissance Technologies
New York
$533K +$1.04M +9,706 +203%
UOC
32
UBS O'Connor
Illinois
$529K +$1.54M +14,385 New
OQS
33
Occudo Quantitative Strategies
Florida
$521K +$1.51M +14,189 New
EC
34
EcoR1 Capital
California
$515K +$1.49M +14,007 New
SSA
35
Schonfeld Strategic Advisors
New York
$423K +$1.23M +11,532 New
UBS Group
36
UBS Group
Switzerland
$384K +$603K +5,652 +118%
CSS
37
Cubist Systematic Strategies
Connecticut
$294K +$739K +6,921 +646%
RJA
38
Raymond James & Associates
Florida
$288K -$5.66K -53 -0.7%
Los Angeles Capital Management
39
Los Angeles Capital Management
California
$263K +$764K +7,163 New
Bank of New York Mellon
40
Bank of New York Mellon
New York
$254K -$41.1K -385 -5%
ECM
41
ExodusPoint Capital Management
New York
$254K +$739K +6,921 New
Point72 Asset Management
42
Point72 Asset Management
Connecticut
$245K -$8.74M -81,929 -92%
Jane Street
43
Jane Street
New York
$238K +$690K +6,462 New
D.E. Shaw & Co
44
D.E. Shaw & Co
New York
$237K +$690K +6,462 New
Swiss National Bank
45
Swiss National Bank
Switzerland
$210K +$233K +2,180 +62%
ECM
46
Endurant Capital Management
California
$194K -$2.56K -24 -0.5%
TCM
47
Tekla Capital Management
Massachusetts
$184K – – –
Susquehanna International Group
48
Susquehanna International Group
Pennsylvania
$181K +$398K +3,726 +307%
XT
49
XTX Topco
Cayman Islands
$174K +$507K +4,746 New
GCM
50
Graham Capital Management
Connecticut
$132K +$384K +3,601 New
1
2
3 4 5

PRAX Hedge Fund Activity: Q2 2022 in Review

95 of the 5,936 institutional investors tracked by Wall St. Rank reported a position in Praxis Precision Medicines (PRAX) for Q2 2022, worth a combined $106M — down 77% from $463M a quarter earlier.

Sellers outnumbered buyers: 27 funds closed out of PRAX and 21 opened new positions — a net loss of 6 holders — while 20 trimmed existing stakes and 37 added.

The largest buyer was State Street, adding an estimated $26.4M. The largest seller was Janus Henderson Group, exiting entirely with an estimated $34M sold.

  • 95 institutional investors held Praxis Precision Medicines (PRAX) as of Q2 2022, down from 103 in Q1 2022.
  • Funds reported $106M of Praxis Precision Medicines stock for Q2 2022, down 77% quarter-over-quarter.
  • 21 funds opened new Praxis Precision Medicines positions in Q2 2022 and 27 closed out, a net change of -6 holders.
  • The largest Praxis Precision Medicines buyer in Q2 2022 was State Street, an estimated $26.4M added.
  • The largest Praxis Precision Medicines seller in Q2 2022 was Janus Henderson Group, an estimated $34M sold.

Based on aggregated 13F filings for Q2 2022.