Renaissance Technologies
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Renaissance Technologies’s Praxis Precision Medicines PRAX Stock Holding History

Renaissance Technologies’s Portfolio PRAX Stock Details PRAX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-66,230
Closed -$19.5M – 3595
2025
Q4 		$19.5M Buy
+66,230
New +$12.3M 0.03% 613
2024
Q3 		– Sell
-75,433
Closed -$3.12M – 3805
2024
Q2 		$3.12M Buy
75,433
+63,329
+523% +$2.99M 0.01% 1588
2024
Q1 		$739K Sell
12,104
-68,700
-85% -$3.08M ﹤0.01% 2673
2023
Q4 		$1.8M Buy
80,804
+15,671
+24% +$282K ﹤0.01% 2017
2023
Q3 		$1.67M Buy
65,133
+21,413
+49% +$405K ﹤0.01% 1971
2023
Q2 		$754K Buy
43,720
+18,387
+73% +$282K ﹤0.01% 2652
2023
Q1 		$307K Buy
25,333
+1,066
+4% +$45K ﹤0.01% 3107
2022
Q4 		$866K Sell
24,267
-5,674
-19% -$177K ﹤0.01% 2615
2022
Q3 		$1.02M Buy
29,941
+15,448
+107% +$770K ﹤0.01% 2487
2022
Q2 		$533K Buy
14,493
+9,706
+203% +$1.04M ﹤0.01% 3131
2022
Q1 		$733K Buy
4,787
+3,914
+448% +$804K ﹤0.01% 2933
2021
Q4 		$258K Buy
+873
New +$256K ﹤0.01% 3409
2021
Q3 		– Sell
-2,493
Closed -$684K – 3760
2021
Q2 		$684K Buy
+2,493
New +$893K ﹤0.01% 2831

Other funds holding PRAX

Janus Henderson Group
Janus Henderson Group London $209B AUM 37.72% 1-Year Est. Return
OAG
Orbis Allan Gray Hamilton, Bermuda $29.1B AUM 60.8% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
DM
Deerfield Management New York $9.59B AUM 113.36% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
CAM
Cormorant Asset Management Boston, Massachusetts $1.95B AUM 773.9% 1-Year Est. Return

Renaissance Technologies's PRAX Position: Q1 2026 in Review

Renaissance Technologies sold out of Praxis Precision Medicines (PRAX) in Q1 2026, closing a stake of 66,230 shares — an estimated $19.5M sold.

Renaissance Technologies first reported a position in PRAX in Q2 2021 and held it in 13 quarters. The position peaked at $19.5M in Q4 2025. 291 funds tracked by Wall St. Rank hold PRAX as of Q1 2026.

  • Renaissance Technologies reported no remaining Praxis Precision Medicines position as of Q1 2026 after selling out during the quarter.
  • Renaissance Technologies sold 66,230 Praxis Precision Medicines shares in Q1 2026, an estimated $19.5M.
  • Renaissance Technologies first reported a position in Praxis Precision Medicines in Q2 2021 and held it in 13 quarters.
  • Renaissance Technologies's Praxis Precision Medicines position peaked at $19.5M in Q4 2025.
  • 291 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q1 2026.

Based on Renaissance Technologies's 13F filing for Q1 2026, filed 14 May 2026.