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Praxis Precision Medicines

250 hedge funds and large institutions have $8.69B invested in Praxis Precision Medicines in 2025 Q4 according to their latest regulatory filings, with 115 funds opening new positions, 87 increasing their positions, 44 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

700% more funds holding in top 10

Funds holding in top 10: 324 (+21)

667% more first-time investments, than exits

New positions opened: 115 | Existing positions closed: 15

564% more capital invested

Capital invested by funds: $1.31B → $8.69B (+$7.38B)

98% more repeat investments, than reductions

Existing positions increased: 87 | Existing positions reduced: 44

64% more funds holding

Funds holding: 152250 (+98)

0.66% more ownership

Funds ownership: 117.18%117.84% (+0.66%)

8% less call options, than puts

Call options by funds: $219M | Put options by funds: $238M

Holders
250
Holders Change
+98
Holders Change %
+64.47%
% of All Funds
3.04%
Holding in Top 10
24
Holding in Top 10 Change
+21
Holding in Top 10 Change %
+700%
% of All Funds
0.29%
New
115
Increased
87
Reduced
44
Closed
15
Calls
$219M
Puts
$238M
Net Calls
-$18.3M
Net Calls Change
-$22.9M
Name Holding Trade Value Shares
Change
Change in
Stake
5VM
251
5AM Venture Management
California
-$9.01M -170,000 Closed
KCM
252
Kennedy Capital Management
Missouri
-$4.04M -76,218 Closed
TLP
253
Tri Locum Partners
New York
-$4.03M -75,986 Closed
SFM
254
Sphera Funds Management
Israel
-$10.8M -57,901 Closed
Jane Street
255
Jane Street
New York
-$5.9M -31,687 Closed
DMKJ
256
David M. Knott Jr
-$1.48M -28,000 Closed
Simplex Trading
257
Simplex Trading
Illinois
-$1.19M -22,529 Closed
DFCM
258
Dark Forest Capital Management
Puerto Rico
-$1.15M -21,684 Closed
PWA
259
PCG Wealth Advisors
Kansas
-$768K -14,483 Closed
AA
260
ALPS Advisors
Colorado
-$552K -10,424 Closed
FGP
261
Freestone Grove Partners
California
-$438K -8,269 Closed
PF
262
Phoenix Financial
Israel
-$362K -6,817 Closed
GCP
263
GSA Capital Partners
United Kingdom
-$304K -5,740 Closed
JFG
264
Jefferies Financial Group
New York
-$106K -2,000 Closed
SSG
265
Summit Securities Group
New York
-$8.69K -164 Closed