|
1
|
Frazier Life Sciences Management
Palo Alto,
California
|
$346M
|
–
|
–
|
–
|
|
|
2
|
Janus Henderson Group
London,
|
$266M
|
+$20.9M
|
+470,168
|
+10%
|
|
|
3
|
|
$182M
|
+$10.6M
|
+237,534
|
+7%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$141M
|
-$1.57M
|
-35,180
|
-1%
|
|
|
5
|
Eventide Asset Management
Boston,
Massachusetts
|
$134M
|
+$4.92M
|
+110,485
|
+4%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$131M
|
+$1.1M
|
+24,808
|
+1%
|
|
|
7
|
Novo Holdings A/S
Hellerup,
Denmark
|
$76.3M
|
+$2.45K
|
+55
|
+0%
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$72.1M
|
+$92.5K
|
+2,078
|
+0.1%
|
|
|
9
|
Citadel Advisors
Miami,
Florida
|
$71.6M
|
-$1.77M
|
-39,643
|
-3%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$70M
|
-$5.3M
|
-118,938
|
-8%
|
|
|
11
|
Tang Capital Management
San Diego,
California
|
$62.9M
|
-$48.1K
|
-1,080
|
-0.1%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$52.4M
|
+$2.94M
|
+65,951
|
+7%
|
|
|
13
|
ClearBridge Investments
New York
|
$52.3M
|
+$2.2M
|
+49,460
|
+5%
|
|
|
14
|
Polar Capital Holdings
London,
United Kingdom
|
$49.6M
|
-$8.9M
|
-200,000
|
-17%
|
|
|
15
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$41.6M
|
-$5.95M
|
-133,559
|
-14%
|
|
|
16
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$39.2M
|
-$1.88M
|
-42,252
|
-5%
|
|
|
17
|
Pictet Asset Management
Carouge,
Switzerland
|
$35.7M
|
-$3.43M
|
-77,088
|
-10%
|
|
|
18
|
Boone Capital Management
Atlanta,
Georgia
|
$32.6M
|
+$1.7M
|
+38,130
|
+6%
|
|
|
19
|
Franklin Resources
San Mateo,
California
|
$30.2M
|
+$10.7K
|
+241
|
+0%
|
|
|
20
|
Nuveen
Charlotte,
North Carolina
|
$30M
|
-$2.87M
|
-64,465
|
-10%
|
|
|
21
|
Woodline Partners
San Francisco,
California
|
$28.9M
|
+$72.3K
|
+1,623
|
+0.3%
|
|
|
22
|
|
$28.8M
|
-$1.79M
|
-40,105
|
-7%
|
|
|
23
|
|
$28.2M
|
+$520K
|
+11,680
|
+2%
|
|
|
24
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$28.1M
|
-$588K
|
-13,198
|
-2%
|
|
|
25
|
First Turn Management
Del Mar,
California
|
$26.8M
|
+$1.09M
|
+24,526
|
+5%
|
|
