|
1
|
Frazier Life Sciences Management
Palo Alto,
California
|
$163M
|
–
|
–
|
–
|
|
|
2
|
BVF Inc
San Francisco,
California
|
$110M
|
–
|
–
|
–
|
|
|
3
|
Eventide Asset Management
Boston,
Massachusetts
|
$82.9M
|
+$17.5M
|
+636,751
|
+24%
|
|
|
4
|
State Street
Boston,
Massachusetts
|
$70.9M
|
+$29.9M
|
+1,087,697
|
+63%
|
|
|
5
|
Janus Henderson Group
London,
|
$69.5M
|
+$19.4M
|
+704,659
|
+34%
|
|
|
6
|
|
$61.6M
|
-$261K
|
-9,477
|
-0.4%
|
|
|
7
|
Cadian Capital Management
New York
|
$57.6M
|
+$9.83M
|
+357,645
|
+18%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$55.6M
|
-$7.27M
|
-264,559
|
-11%
|
|
|
9
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$46.6M
|
+$140K
|
+5,100
|
+0.3%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$40.1M
|
+$11.9M
|
+432,824
|
+37%
|
|
|
11
|
Novo Holdings A/S
Hellerup,
Denmark
|
$37.7M
|
–
|
–
|
–
|
|
|
12
|
Citadel Advisors
Miami,
Florida
|
$35M
|
-$1.38M
|
-50,306
|
-3%
|
|
|
13
|
Tang Capital Management
San Diego,
California
|
$29.8M
|
+$1.37M
|
+50,000
|
+4%
|
|
|
14
|
Avidity Partners Management
Dallas,
Texas
|
$28.7M
|
–
|
–
|
–
|
|
|
15
|
First Turn Management
Del Mar,
California
|
$24.1M
|
+$3.36M
|
+122,352
|
+15%
|
|
|
16
|
Pictet Asset Management
Carouge,
Switzerland
|
$24M
|
+$4.46M
|
+162,259
|
+20%
|
|
|
17
|
Franklin Resources
San Mateo,
California
|
$23.6M
|
+$778K
|
+28,306
|
+3%
|
|
|
18
|
|
$17.6M
|
+$6.7M
|
+243,798
|
+53%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$17.5M
|
+$439K
|
+15,959
|
+2%
|
|
|
20
|
William Blair Investment Management
Chicago,
Illinois
|
$15.8M
|
+$151K
|
+5,494
|
+0.9%
|
|
|
21
|
Polar Capital Holdings
London,
United Kingdom
|
$15.7M
|
–
|
–
|
–
|
|
|
22
|
|
$14.9M
|
+$2.01K
|
+73
|
+0%
|
|
|
23
|
Millennium Management
New York
|
$13.6M
|
+$8.67M
|
+315,290
|
+141%
|
|
|
24
|
Prosight Management
Dallas,
Texas
|
$11.7M
|
+$4.72M
|
+171,699
|
+59%
|
|
|
25
|
Boone Capital Management
Atlanta,
Georgia
|
$11.4M
|
-$1.05M
|
-38,241
|
-8%
|
|
