|
1
|
Frazier Life Sciences Management
Palo Alto,
California
|
$306M
|
+$10.6M
|
+224,729
|
+3%
|
|
|
2
|
Janus Henderson Group
London,
|
$219M
|
+$8.69M
|
+184,467
|
+4%
|
|
|
3
|
|
$150M
|
-$4.48M
|
-95,071
|
-3%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$126M
|
–
|
–
|
–
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$114M
|
+$5.44M
|
+115,327
|
+5%
|
|
|
6
|
Eventide Asset Management
Boston,
Massachusetts
|
$114M
|
-$3.77M
|
-79,938
|
-3%
|
|
|
7
|
Novo Holdings A/S
Hellerup,
Denmark
|
$67.6M
|
–
|
–
|
–
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$67.3M
|
+$5.32M
|
+112,939
|
+8%
|
|
|
9
|
Citadel Advisors
Miami,
Florida
|
$65.1M
|
-$3.07M
|
-65,188
|
-4%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$63.8M
|
-$358K
|
-7,592
|
-0.5%
|
|
|
11
|
Tang Capital Management
San Diego,
California
|
$55.7M
|
–
|
–
|
–
|
|
|
12
|
Polar Capital Holdings
London,
United Kingdom
|
$52.9M
|
+$23.6M
|
+500,000
|
+74%
|
|
|
13
|
ClearBridge Investments
New York
|
$44.1M
|
+$3.33M
|
+70,750
|
+8%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$43.4M
|
+$958K
|
+20,321
|
+2%
|
|
|
15
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$42.9M
|
-$24.5M
|
-519,799
|
-35%
|
|
|
16
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$36.6M
|
+$1.46M
|
+31,044
|
+4%
|
|
|
17
|
Pictet Asset Management
Carouge,
Switzerland
|
$35.1M
|
-$3.86M
|
-81,852
|
-10%
|
|
|
18
|
Nuveen
Charlotte,
North Carolina
|
$29.5M
|
-$3.18M
|
-67,433
|
-9%
|
|
|
19
|
|
$27.3M
|
-$7.16M
|
-151,949
|
-20%
|
|
|
20
|
Boone Capital Management
Atlanta,
Georgia
|
$27.2M
|
+$1.01M
|
+21,475
|
+4%
|
|
|
21
|
Franklin Resources
San Mateo,
California
|
$26.7M
|
+$127K
|
+2,693
|
+0.5%
|
|
|
22
|
Woodline Partners
San Francisco,
California
|
$25.5M
|
+$7.63M
|
+161,867
|
+40%
|
|
|
23
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$25.5M
|
-$559K
|
-11,869
|
-2%
|
|
|
24
|
|
$24.5M
|
+$18.2M
|
+385,925
|
+245%
|
|
|
25
|
First Turn Management
Del Mar,
California
|
$22.7M
|
-$184K
|
-3,894
|
-0.8%
|
|
