|
1
|
Frazier Life Sciences Management
Palo Alto,
California
|
$192M
|
+$757K
|
+25,000
|
+0.4%
|
|
|
2
|
BVF Inc
San Francisco,
California
|
$129M
|
–
|
–
|
–
|
|
|
3
|
Eventide Asset Management
Boston,
Massachusetts
|
$78.6M
|
-$39.2M
|
-1,294,930
|
-33%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$73.1M
|
+$23.7M
|
+782,901
|
+46%
|
|
|
5
|
|
$72.7M
|
+$10.5M
|
+348,341
|
+16%
|
|
|
6
|
Janus Henderson Group
London,
|
$60.9M
|
+$4.2M
|
+138,791
|
+7%
|
|
|
7
|
Cadian Capital Management
New York
|
$57.1M
|
+$15.1M
|
+500,000
|
+35%
|
|
|
8
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$54.7M
|
+$930K
|
+30,731
|
+2%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$51.2M
|
+$3.45M
|
+113,865
|
+7%
|
|
|
10
|
Novo Holdings A/S
Hellerup,
Denmark
|
$44.3M
|
–
|
–
|
–
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$42.6M
|
-$8.31M
|
-274,445
|
-16%
|
|
|
12
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$34.4M
|
+$34.3M
|
+1,132,723
|
+3,544%
|
|
|
13
|
Avidity Partners Management
Dallas,
Texas
|
$33.7M
|
–
|
–
|
–
|
|
|
14
|
Tang Capital Management
San Diego,
California
|
$33.6M
|
–
|
–
|
–
|
|
|
15
|
Franklin Resources
San Mateo,
California
|
$27M
|
+$5.1M
|
+168,446
|
+23%
|
|
|
16
|
First Turn Management
Del Mar,
California
|
$24.7M
|
+$25.3M
|
+836,302
|
New
|
|
|
17
|
Pictet Asset Management
Carouge,
Switzerland
|
$23.4M
|
+$1.65M
|
+54,645
|
+7%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$20.1M
|
+$3.21M
|
+106,100
|
+18%
|
|
|
19
|
Polar Capital Holdings
London,
United Kingdom
|
$18.4M
|
-$16.6M
|
-550,000
|
-47%
|
|
|
20
|
William Blair Investment Management
Chicago,
Illinois
|
$18.4M
|
+$2.67M
|
+88,085
|
+17%
|
|
|
21
|
|
$17.5M
|
-$708K
|
-23,402
|
-4%
|
|
|
22
|
Adage Capital Partners
Boston,
Massachusetts
|
$17M
|
-$2.72M
|
-90,000
|
-14%
|
|
|
23
|
Perceptive Advisors
New York
|
$15.8M
|
-$4.15M
|
-137,100
|
-20%
|
|
|
24
|
Boone Capital Management
Atlanta,
Georgia
|
$14.5M
|
+$3.04M
|
+100,348
|
+26%
|
|
|
25
|
Nuveen
Charlotte,
North Carolina
|
$13.9M
|
+$1.14M
|
+37,557
|
+9%
|
|
