|
1
|
Frazier Life Sciences Management
Palo Alto,
California
|
$272M
|
–
|
–
|
–
|
|
|
2
|
Janus Henderson Group
London,
|
$189M
|
+$4.22M
|
+101,358
|
+2%
|
|
|
3
|
|
$142M
|
+$2.77M
|
+66,471
|
+2%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$116M
|
-$11.6M
|
-279,394
|
-9%
|
|
|
5
|
Eventide Asset Management
Boston,
Massachusetts
|
$108M
|
-$34.9M
|
-838,425
|
-24%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$100M
|
-$2.97M
|
-71,378
|
-3%
|
|
|
7
|
Citadel Advisors
Miami,
Florida
|
$62.5M
|
+$4.99M
|
+119,774
|
+9%
|
|
|
8
|
Novo Holdings A/S
Hellerup,
Denmark
|
$62M
|
–
|
–
|
–
|
|
|
9
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$60.8M
|
-$4.54M
|
-108,924
|
-7%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$58.8M
|
+$5.78M
|
+138,623
|
+11%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$57.1M
|
-$17.2M
|
-412,101
|
-23%
|
|
|
12
|
Tang Capital Management
San Diego,
California
|
$51.2M
|
-$2.08M
|
-50,000
|
-4%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$39M
|
+$298K
|
+7,147
|
+0.8%
|
|
|
14
|
ClearBridge Investments
New York
|
$37.5M
|
+$759K
|
+18,217
|
+2%
|
|
|
15
|
Pictet Asset Management
Carouge,
Switzerland
|
$35.6M
|
-$1.48M
|
-35,594
|
-4%
|
|
|
16
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$32.4M
|
+$1.71M
|
+40,986
|
+6%
|
|
|
17
|
|
$31.4M
|
+$5.52M
|
+132,464
|
+21%
|
|
|
18
|
Nuveen
Charlotte,
North Carolina
|
$29.9M
|
+$9.57M
|
+229,746
|
+47%
|
|
|
19
|
Polar Capital Holdings
London,
United Kingdom
|
$27.9M
|
–
|
–
|
–
|
|
|
20
|
Avidity Partners Management
Dallas,
Texas
|
$27.5M
|
-$2.7M
|
-64,904
|
-9%
|
|
|
21
|
Franklin Resources
San Mateo,
California
|
$24.4M
|
-$83.1K
|
-1,994
|
-0.3%
|
|
|
22
|
MPM BioImpact
Boston,
Massachusetts
|
$24.4M
|
+$4.04M
|
+96,856
|
+20%
|
|
|
23
|
Boone Capital Management
Atlanta,
Georgia
|
$24.1M
|
+$1.58M
|
+38,000
|
+7%
|
|
|
24
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$23.9M
|
+$3.28M
|
+78,708
|
+16%
|
|
|
25
|
|
$23M
|
-$3.43M
|
-82,331
|
-13%
|
|
