|
1
|
Frazier Life Sciences Management
Palo Alto,
California
|
$222M
|
–
|
–
|
–
|
|
|
2
|
Janus Henderson Group
London,
|
$171M
|
+$58.2M
|
+2,221,537
|
+80%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$149M
|
–
|
–
|
–
|
|
|
4
|
Eventide Asset Management
Boston,
Massachusetts
|
$124M
|
+$8.24M
|
+314,420
|
+10%
|
|
|
5
|
|
$111M
|
+$20.6M
|
+785,776
|
+32%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$83.7M
|
+$6.16M
|
+235,048
|
+11%
|
|
|
7
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$60.6M
|
-$2.22M
|
-84,526
|
-5%
|
|
|
8
|
Citadel Advisors
Miami,
Florida
|
$54.2M
|
+$5.06M
|
+193,118
|
+14%
|
|
|
9
|
Novo Holdings A/S
Hellerup,
Denmark
|
$51.3M
|
–
|
–
|
–
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$51.2M
|
-$34.8M
|
-1,326,255
|
-47%
|
|
|
11
|
Tang Capital Management
San Diego,
California
|
$44M
|
+$2.62M
|
+100,000
|
+8%
|
|
|
12
|
Cadian Capital Management
New York
|
$42.2M
|
-$27.7M
|
-1,057,446
|
-46%
|
|
|
13
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$41M
|
-$10.4M
|
-398,286
|
-25%
|
|
|
14
|
Franklin Resources
San Mateo,
California
|
$32.2M
|
+$5.14K
|
+196
|
+0%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$31M
|
+$5.51M
|
+210,041
|
+30%
|
|
|
16
|
Pictet Asset Management
Carouge,
Switzerland
|
$29.9M
|
-$2.12M
|
-80,801
|
-8%
|
|
|
17
|
|
$26M
|
+$1.54M
|
+58,902
|
+8%
|
|
|
18
|
Polar Capital Holdings
London,
United Kingdom
|
$25.3M
|
+$3.04M
|
+116,049
|
+19%
|
|
|
19
|
Avidity Partners Management
Dallas,
Texas
|
$25M
|
-$10.8M
|
-411,746
|
-36%
|
|
|
20
|
First Turn Management
Del Mar,
California
|
$24M
|
-$6.69M
|
-255,256
|
-27%
|
|
|
21
|
ClearBridge Investments
New York
|
$23.9M
|
+$11.4M
|
+436,349
|
+166%
|
|
|
22
|
William Blair Investment Management
Chicago,
Illinois
|
$23.2M
|
+$1.33M
|
+50,667
|
+8%
|
|
|
23
|
|
$18.5M
|
+$4.89M
|
+186,434
|
+53%
|
|
|
24
|
Boone Capital Management
Atlanta,
Georgia
|
$17.9M
|
+$1.88M
|
+71,781
|
+16%
|
|
|
25
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$17.4M
|
+$13.3M
|
+508,475
|
New
|
|
