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LYRA

LYRA THERAPEUTICS INC

Delisted

LYRA was delisted on the 16th of March, 2026.

51 hedge funds and large institutions have $9.06M invested in LYRA THERAPEUTICS INC in 2024 Q2 according to their latest regulatory filings, with 15 funds opening new positions, 14 increasing their positions, 13 reducing their positions, and 42 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more repeat investments, than reductions

Existing positions increased: 14 | Existing positions reduced: 13

0.45% less ownership

Funds ownership: 1.53%1.07% (-0.45%)

35% less funds holding

Funds holding: 7851 (-27)

64% less first-time investments, than exits

New positions opened: 15 | Existing positions closed: 42

97% less capital invested

Capital invested by funds: $283M → $9.06M (-$274M)

100% less funds holding in top 10

Funds holding in top 10: 30 (-3)

Holders
51
Holders Change
-27
Holders Change %
-34.62%
% of All Funds
0.74%
Holding in Top 10
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-100%
% of All Funds
New
15
Increased
14
Reduced
13
Closed
42
Calls
$88K
Puts
Net Calls
+$88K
Net Calls Change
-$1.77M
Name Holding Trade Value Shares
Change
Change in
Stake
PA
1
Perceptive Advisors
New York
$3.53M
Citadel Advisors
2
Citadel Advisors
Florida
$1.32M +$981K +8,674 +10%
BlackRock
3
BlackRock
New York
$783K +$6.06M +53,562 +1,763%
SB
4
Samsara BioCapital
California
$769K
Vanguard Group
5
Vanguard Group
Pennsylvania
$479K +$564K +4,988 +17%
IC
6
Ikarian Capital
Texas
$292K
RA
7
Rosalind Advisors
Ontario, Canada
$286K -$248K -2,195 -10%
Acadian Asset Management
8
Acadian Asset Management
Massachusetts
$271K +$2.23M +19,713 New
Morgan Stanley
9
Morgan Stanley
New York
$225K +$1.69M +14,947 +1,160%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$209K +$895K +7,913 +110%
Two Sigma Advisers
11
Two Sigma Advisers
New York
$189K +$1.22M +10,754 +374%
Two Sigma Investments
12
Two Sigma Investments
New York
$136K +$694K +6,142 +167%
New York State Common Retirement Fund
13
New York State Common Retirement Fund
New York
$106K +$866K +7,658 New
State Street
14
State Street
Massachusetts
$71.9K +$302K +2,672 +106%
BFM
15
Boothbay Fund Management
New York
$64.4K
Simplex Trading
16
Simplex Trading
Illinois
$35K +$292K +2,583 New
CC
17
Clearline Capital
New York
$33K
Charles Schwab
18
Charles Schwab
California
$30.9K +$252K +2,232 New
Bank of America
19
Bank of America
North Carolina
$23.9K -$165K -1,463 -46%
Northern Trust
20
Northern Trust
Illinois
$23.2K +$52.8K +467 +39%
Bank of New York Mellon
21
Bank of New York Mellon
New York
$21.4K +$175K +1,548 New
AGM
22
Alpine Global Management
New York
$12.8K +$105K +929 New
RhumbLine Advisers
23
RhumbLine Advisers
Massachusetts
$12K +$97.4K +862 +14,367%
Jane Street
24
Jane Street
New York
$11.8K -$260K -2,300 -73%
Susquehanna International Group
25
Susquehanna International Group
Pennsylvania
$9.73K -$697K -6,163 -90%

LYRA Hedge Fund Activity: Q2 2024 in Review

51 of the 6,926 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q2 2024, worth a combined $9.06M — down 97% from $283M a quarter earlier.

Sellers outnumbered buyers: 42 funds closed out of LYRA and 15 opened new positions — a net loss of 27 holders — while 13 trimmed existing stakes and 14 added.

The largest buyer was BlackRock, adding an estimated $6.06M. The largest seller was Nantahala Capital Management, exiting entirely with an estimated $17.5M sold.

  • 51 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q2 2024, down from 78 in Q1 2024.
  • Funds reported $9.06M of LYRA THERAPEUTICS INC stock for Q2 2024, down 97% quarter-over-quarter.
  • 15 funds opened new LYRA THERAPEUTICS INC positions in Q2 2024 and 42 closed out, a net change of -27 holders.
  • The largest LYRA THERAPEUTICS INC buyer in Q2 2024 was BlackRock, an estimated $6.06M added.
  • The largest LYRA THERAPEUTICS INC seller in Q2 2024 was Nantahala Capital Management, an estimated $17.5M sold.

Based on aggregated 13F filings for Q2 2024.