LYRA THERAPEUTICS INC
LYRA
LYRA was delisted on the 16th of March, 2026.
44 hedge funds and large institutions have $55.9M invested in LYRA THERAPEUTICS INC in 2021 Q2 according to their latest regulatory filings, with 11 funds opening new positions, 3 increasing their positions, 21 reducing their positions, and 16 closing their positions.
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
0.09% less ownership
Funds ownership: 1.17% → 1.07% (-0.09%)
10% less funds holding
Funds holding: 49 → 44 (-5)
31% less first-time investments, than exits
New positions opened: 11 | Existing positions closed: 16
36% less capital invested
Capital invested by funds: $87.6M → $55.9M (-$31.7M)
86% less repeat investments, than reductions
Existing positions increased: 3 | Existing positions reduced: 21
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
PVI
Pura Vida Investments
New York
|
+$4.94M |
| 2 |
Millennium Management
New York
|
+$1.41M |
| 3 |
TEE
Tibra Equities Europe
London,
United Kingdom
|
+$364K |
| 4 |
ECM
ExodusPoint Capital Management
New York
|
+$287K |
| 5 |
E
Ergoteles
New York
|
+$282K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BlackRock
New York
|
-$2.99M |
| 2 |
SCM
Soleus Capital Management
Greenwich,
Connecticut
|
-$2.67M |
| 3 |
IC
Ikarian Capital
Dallas,
Texas
|
-$1.42M |
| 4 |
JP Morgan Chase
New York
|
-$1.34M |
| 5 |
State Street
Boston,
Massachusetts
|
-$1.11M |
LYRA Hedge Fund Activity: Q2 2021 in Review
44 of the 5,746 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q2 2021, worth a combined $55.9M — down 36% from $87.6M a quarter earlier.
Sellers outnumbered buyers: 16 funds closed out of LYRA and 11 opened new positions — a net loss of 5 holders — while 21 trimmed existing stakes and 3 added.
The largest buyer was Pura Vida Investments, opening a new position worth an estimated $4.94M. The largest seller was BlackRock, cutting an estimated $2.99M.
- 44 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q2 2021, down from 49 in Q1 2021.
- Funds reported $55.9M of LYRA THERAPEUTICS INC stock for Q2 2021, down 36% quarter-over-quarter.
- 11 funds opened new LYRA THERAPEUTICS INC positions in Q2 2021 and 16 closed out, a net change of -5 holders.
- The largest LYRA THERAPEUTICS INC buyer in Q2 2021 was Pura Vida Investments, an estimated $4.94M added.
- The largest LYRA THERAPEUTICS INC seller in Q2 2021 was BlackRock, an estimated $2.99M sold.
Based on aggregated 13F filings for Q2 2021.