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LYRA

LYRA THERAPEUTICS INC

Delisted

LYRA was delisted on the 16th of March, 2026.

49 hedge funds and large institutions have $87.6M invested in LYRA THERAPEUTICS INC in 2021 Q1 according to their latest regulatory filings, with 10 funds opening new positions, 13 increasing their positions, 13 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

150% more first-time investments, than exits

New positions opened: 10 | Existing positions closed: 4

14% more funds holding

Funds holding: 4349 (+6)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

0% more repeat investments, than reductions

Existing positions increased: 13 | Existing positions reduced: 13

0.16% less ownership

Funds ownership: 1.33%1.17% (-0.16%)

11% less capital invested

Capital invested by funds: $97.9M → $87.6M (-$10.4M)

Holders
49
Holders Change
+6
Holders Change %
+13.95%
% of All Funds
0.86%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
10
Increased
13
Reduced
13
Closed
4
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
PA
1
Perceptive Advisors
New York
$37.3M
PVMCV
2
Polaris Venture Management Co V
Massachusetts
$12.8M
IC
3
Ikarian Capital
Texas
$9.05M -$432K -692 -4%
SCM
4
Soleus Capital Management
Connecticut
$5.51M +$246K +393 +4%
BlackRock
5
BlackRock
New York
$4.04M +$1.05M +1,685 +32%
Vanguard Group
6
Vanguard Group
Pennsylvania
$2.46M +$477K +764 +22%
JP Morgan Chase
7
JP Morgan Chase
New York
$1.71M -$545K -872 -23%
ACH
8
ArrowMark Colorado Holdings
Colorado
$1.61M -$7.96M -12,734 -82%
Morgan Stanley
9
Morgan Stanley
New York
$1.24M +$1.16M +1,860 +655%
State Street
10
State Street
Massachusetts
$1.11M +$232K +372 +24%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$1.05M +$272K +436 +32%
BFM
12
Boothbay Fund Management
New York
$970K -$46.2K -74 -4%
Deutsche Bank
13
Deutsche Bank
Germany
$936K +$950K +1,521 +1,601%
Two Sigma Investments
14
Two Sigma Investments
New York
$835K +$619K +991 +220%
Northern Trust
15
Northern Trust
Illinois
$746K -$44.4K -71 -5%
AllianceBernstein
16
AllianceBernstein
Tennessee
$711K
William Blair & Company
17
William Blair & Company
Illinois
$637K +$687K +1,100 New
BCM
18
Bridgeway Capital Management
Texas
$568K
Marshall Wace
19
Marshall Wace
United Kingdom
$544K +$411K +658 +234%
Osaic Holdings
20
Osaic Holdings
Arizona
$491K +$512K +820 +2,733%
Ensign Peak Advisors
21
Ensign Peak Advisors
Utah
$454K
Envestnet Asset Management
22
Envestnet Asset Management
Illinois
$426K +$460K +736 New
Bank of America
23
Bank of America
North Carolina
$374K +$134K +214 +49%
Two Sigma Advisers
24
Two Sigma Advisers
New York
$364K +$393K +629 New
PCM
25
Pentwater Capital Management
Florida
$276K

LYRA Hedge Fund Activity: Q1 2021 in Review

49 of the 5,696 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q1 2021, worth a combined $87.6M — down 11% from $97.9M a quarter earlier.

Buyers outnumbered sellers: 10 funds opened new LYRA positions and 4 closed out — a net gain of 6 holders — while 13 added to existing stakes and 13 trimmed.

The largest buyer was Morgan Stanley, adding an estimated $1.16M. The largest seller was RA Capital Management, exiting entirely with an estimated $9.3M sold.

  • 49 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q1 2021, up from 43 in Q4 2020.
  • Funds reported $87.6M of LYRA THERAPEUTICS INC stock for Q1 2021, down 11% quarter-over-quarter.
  • 10 funds opened new LYRA THERAPEUTICS INC positions in Q1 2021 and 4 closed out, a net change of +6 holders.
  • The largest LYRA THERAPEUTICS INC buyer in Q1 2021 was Morgan Stanley, an estimated $1.16M added.
  • The largest LYRA THERAPEUTICS INC seller in Q1 2021 was RA Capital Management, an estimated $9.3M sold.

Based on aggregated 13F filings for Q1 2021.