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LYRA

LYRA THERAPEUTICS INC

Delisted

LYRA was delisted on the 16th of March, 2026.

33 hedge funds and large institutions have $22.4M invested in LYRA THERAPEUTICS INC in 2021 Q4 according to their latest regulatory filings, with 7 funds opening new positions, 6 increasing their positions, 11 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

0.24% less ownership

Funds ownership: 1.03%0.79% (-0.24%)

6% less funds holding

Funds holding: 3533 (-2)

13% less first-time investments, than exits

New positions opened: 7 | Existing positions closed: 8

45% less repeat investments, than reductions

Existing positions increased: 6 | Existing positions reduced: 11

63% less capital invested

Capital invested by funds: $60.8M → $22.4M (-$38.5M)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
33
Holders Change
-2
Holders Change %
-5.71%
% of All Funds
0.51%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
7
Increased
6
Reduced
11
Closed
8
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
PA
1
Perceptive Advisors
New York
$14.1M
PVI
2
Pura Vida Investments
New York
$2.25M -$104K -323 -3%
IC
3
Ikarian Capital
Texas
$1.72M -$57.2K -178 -2%
Vanguard Group
4
Vanguard Group
Pennsylvania
$954K -$8.35K -26 -0.6%
Millennium Management
5
Millennium Management
New York
$667K +$224K +696 +29%
Bank of America
6
Bank of America
North Carolina
$366K -$171K -533 -24%
PCM
7
Pentwater Capital Management
Florida
$311K +$253K +786 +123%
BCM
8
Bridgeway Capital Management
Texas
$292K -$12.8K -40 -3%
CC
9
Clearline Capital
New York
$283K +$417K +1,297 New
Two Sigma Advisers
10
Two Sigma Advisers
New York
$247K -$8.35K -26 -2%
Renaissance Technologies
11
Renaissance Technologies
New York
$227K +$334K +1,040 New
Ensign Peak Advisors
12
Ensign Peak Advisors
Utah
$171K
BFM
13
Boothbay Fund Management
New York
$168K -$4.5K -14 -2%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$157K
BlackRock
15
BlackRock
New York
$80K +$2.89K +9 +3%
Two Sigma Investments
16
Two Sigma Investments
New York
$77K +$27.9K +87 +32%
Citadel Advisors
17
Citadel Advisors
Florida
$58K +$85.1K +265 New
VF
18
Virtu Financial
New York
$57K +$84.5K +263 New
Susquehanna International Group
19
Susquehanna International Group
Pennsylvania
$49K -$30.2K -94 -30%
TRCT
20
Tower Research Capital (TRC)
New York
$47K +$41.1K +128 +151%
SCM
21
Soleus Capital Management
Connecticut
$44K -$1.32M -4,112 -95%
Morgan Stanley
22
Morgan Stanley
New York
$41K -$133K -414 -69%
CAM
23
Close Asset Management
United Kingdom
$30K
UBS Group
24
UBS Group
Switzerland
$18K +$26K +81 New
Osaic Holdings
25
Osaic Holdings
Arizona
$5K

LYRA Hedge Fund Activity: Q4 2021 in Review

33 of the 6,499 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q4 2021, worth a combined $22.4M — down 63% from $60.8M a quarter earlier.

Sellers outnumbered buyers: 8 funds closed out of LYRA and 7 opened new positions — a net loss of 1 holder — while 11 trimmed existing stakes and 6 added.

The largest buyer was Clearline Capital, opening a new position worth an estimated $417K. The largest seller was Soleus Capital Management, cutting an estimated $1.32M.

  • 33 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q4 2021, down from 35 in Q3 2021.
  • Funds reported $22.4M of LYRA THERAPEUTICS INC stock for Q4 2021, down 63% quarter-over-quarter.
  • 7 funds opened new LYRA THERAPEUTICS INC positions in Q4 2021 and 8 closed out, a net change of -1 holder.
  • The largest LYRA THERAPEUTICS INC buyer in Q4 2021 was Clearline Capital, an estimated $417K added.
  • The largest LYRA THERAPEUTICS INC seller in Q4 2021 was Soleus Capital Management, an estimated $1.32M sold.

Based on aggregated 13F filings for Q4 2021.