We are live on ! Find out more
LYRA

LYRA THERAPEUTICS INC

Delisted

LYRA was delisted on the 16th of March, 2026.

37 hedge funds and large institutions have $96M invested in LYRA THERAPEUTICS INC in 2022 Q3 according to their latest regulatory filings, with 8 funds opening new positions, 7 increasing their positions, 8 reducing their positions, and 7 closing their positions.

New
Increased
Maintained
Reduced
Closed

14% more first-time investments, than exits

New positions opened: 8 | Existing positions closed: 7

3% more funds holding

Funds holding: 3637 (+1)

0.01% less ownership

Funds ownership: 1.21%1.2% (-0.01%)

12% less capital invested

Capital invested by funds: $109M → $96M (-$12.9M)

13% less repeat investments, than reductions

Existing positions increased: 7 | Existing positions reduced: 8

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
37
Holders Change
+1
Holders Change %
+2.78%
% of All Funds
0.64%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
8
Increased
7
Reduced
8
Closed
7
Calls
$66K
Puts
Net Calls
+$66K
Net Calls Change
+$66K
Name Holding Trade Value Shares
Change
Change in
Stake
PA
1
Perceptive Advisors
New York
$45.8M
PVI
2
Pura Vida Investments
New York
$12.6M -$390K -1,318 -3%
NCM
3
Nantahala Capital Management
Connecticut
$11.3M -$732K -2,476 -5%
SB
4
Samsara BioCapital
California
$8.9M
VA
5
VR Adviser
New York
$4.63M
Vanguard Group
6
Vanguard Group
Pennsylvania
$3.96M +$680K +2,299 +17%
SCM
7
Soleus Capital Management
Connecticut
$2.97M
IC
8
Ikarian Capital
Texas
$1.72M -$21.6K -73 -1%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$735K +$156K +527 +22%
CC
10
Clearline Capital
New York
$597K
Bank of America
11
Bank of America
North Carolina
$474K -$16.9K -57 -3%
Ensign Peak Advisors
12
Ensign Peak Advisors
Utah
$317K +$41.1K +139 +12%
BCM
13
Bridgeway Capital Management
Texas
$285K
Two Sigma Advisers
14
Two Sigma Advisers
New York
$214K +$26K +88 +11%
Renaissance Technologies
15
Renaissance Technologies
New York
$200K -$5.92K -20 -2%
BlackRock
16
BlackRock
New York
$196K -$15.4K -52 -6%
Citadel Advisors
17
Citadel Advisors
Florida
$186K +$220K +743 New
State Street
18
State Street
Massachusetts
$176K +$4.73K +16 +2%
BFM
19
Boothbay Fund Management
New York
$174K -$21.6K -73 -10%
Northern Trust
20
Northern Trust
Illinois
$149K
Susquehanna International Group
21
Susquehanna International Group
Pennsylvania
$108K +$127K +431 New
Bank of New York Mellon
22
Bank of New York Mellon
New York
$98K +$115K +390 New
Millennium Management
23
Millennium Management
New York
$95K -$413K -1,396 -79%
TSS
24
Two Sigma Securities
New York
$64K +$75.4K +255 New
HWM
25
HighMark Wealth Management
Minnesota
$20K

LYRA Hedge Fund Activity: Q3 2022 in Review

37 of the 5,806 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q3 2022, worth a combined $96M — down 12% from $109M a quarter earlier.

Buyers outnumbered sellers: 8 funds opened new LYRA positions and 7 closed out — a net gain of 1 holder — while 7 added to existing stakes and 8 trimmed.

The largest buyer was Vanguard Group, adding an estimated $680K. The largest seller was Nantahala Capital Management, cutting an estimated $732K.

  • 37 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q3 2022, up from 36 in Q2 2022.
  • Funds reported $96M of LYRA THERAPEUTICS INC stock for Q3 2022, down 12% quarter-over-quarter.
  • 8 funds opened new LYRA THERAPEUTICS INC positions in Q3 2022 and 7 closed out, a net change of +1 holder.
  • The largest LYRA THERAPEUTICS INC buyer in Q3 2022 was Vanguard Group, an estimated $680K added.
  • The largest LYRA THERAPEUTICS INC seller in Q3 2022 was Nantahala Capital Management, an estimated $732K sold.

Based on aggregated 13F filings for Q3 2022.