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LYRA

LYRA THERAPEUTICS INC

Delisted

LYRA was delisted on the 16th of March, 2026.

44 hedge funds and large institutions have $125M invested in LYRA THERAPEUTICS INC in 2023 Q3 according to their latest regulatory filings, with 10 funds opening new positions, 15 increasing their positions, 7 reducing their positions, and 3 closing their positions.

New
Increased
Maintained
Reduced
Closed

15,983% more call options, than puts

Call options by funds: $965K | Put options by funds: $6K

233% more first-time investments, than exits

New positions opened: 10 | Existing positions closed: 3

114% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 7

19% more funds holding

Funds holding: 3744 (+7)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

0.83% less ownership

Funds ownership: 2.12%1.29% (-0.83%)

10% less capital invested

Capital invested by funds: $138M → $125M (-$13.6M)

Holders
44
Holders Change
+7
Holders Change %
+18.92%
% of All Funds
0.7%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
10
Increased
15
Reduced
7
Closed
3
Calls
$965K
Puts
$6K
Net Calls
+$959K
Net Calls Change
-$40K
Name Holding Trade Value Shares
Change
Change in
Stake
PA
1
Perceptive Advisors
New York
$49.9M
NCM
2
Nantahala Capital Management
Connecticut
$15.8M +$331K +1,853 +2%
Citadel Advisors
3
Citadel Advisors
Florida
$11.1M -$2.33K -13 -0%
SB
4
Samsara BioCapital
California
$10.9M
AC
5
Armistice Capital
New York
$6.06M -$8.81M -49,241 -61%
PVI
6
Pura Vida Investments
New York
$5.53M
IC
7
Ikarian Capital
Texas
$4.9M +$987K +5,515 +28%
VA
8
VR Adviser
New York
$3.61M
Vanguard Group
9
Vanguard Group
Pennsylvania
$3.38M +$263K +1,468 +9%
PHP
10
Parkman Healthcare Partners
Connecticut
$2.44M +$89.6K +501 +4%
SCM
11
Soleus Capital Management
Connecticut
$2.32M
Geode Capital Management
12
Geode Capital Management
Massachusetts
$1.21M +$572K +3,197 +107%
Ensign Peak Advisors
13
Ensign Peak Advisors
Utah
$1.18M -$2.5K -14 -0.2%
Millennium Management
14
Millennium Management
New York
$1.03M +$942K +5,267 New
BFM
15
Boothbay Fund Management
New York
$915K +$252K +1,406 +43%
Susquehanna International Group
16
Susquehanna International Group
Pennsylvania
$637K +$540K +3,019 +1,268%
BCM
17
Bridgeway Capital Management
Texas
$554K +$161K +900 +46%
Alyeska Investment Group
18
Alyeska Investment Group
Illinois
$512K -$1.25M -7,012 -73%
Bank of America
19
Bank of America
North Carolina
$492K +$47K +263 +12%
CC
20
Clearline Capital
New York
$466K
State Street
21
State Street
Massachusetts
$372K +$141K +786 +70%
Citigroup
22
Citigroup
New York
$265K +$242K +1,354 New
Northern Trust
23
Northern Trust
Illinois
$223K +$97.7K +546 +92%
Renaissance Technologies
24
Renaissance Technologies
New York
$195K -$75.8K -424 -30%
BlackRock
25
BlackRock
New York
$186K -$3.94K -22 -2%

LYRA Hedge Fund Activity: Q3 2023 in Review

44 of the 6,302 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q3 2023, worth a combined $125M — down 9.8% from $138M a quarter earlier.

Buyers outnumbered sellers: 10 funds opened new LYRA positions and 3 closed out — a net gain of 7 holders — while 15 added to existing stakes and 7 trimmed.

The largest buyer was Ikarian Capital, adding an estimated $987K. The largest seller was Armistice Capital, cutting an estimated $8.81M.

  • 44 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q3 2023, up from 37 in Q2 2023.
  • Funds reported $125M of LYRA THERAPEUTICS INC stock for Q3 2023, down 9.8% quarter-over-quarter.
  • 10 funds opened new LYRA THERAPEUTICS INC positions in Q3 2023 and 3 closed out, a net change of +7 holders.
  • The largest LYRA THERAPEUTICS INC buyer in Q3 2023 was Ikarian Capital, an estimated $987K added.
  • The largest LYRA THERAPEUTICS INC seller in Q3 2023 was Armistice Capital, an estimated $8.81M sold.

Based on aggregated 13F filings for Q3 2023.