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LYRA

LYRA THERAPEUTICS INC

Delisted

LYRA was delisted on the 16th of March, 2026.

54 hedge funds and large institutions have $5.54M invested in LYRA THERAPEUTICS INC in 2024 Q4 according to their latest regulatory filings, with 8 funds opening new positions, 20 increasing their positions, 11 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

82% more repeat investments, than reductions

Existing positions increased: 20 | Existing positions reduced: 11

0.17% less ownership

Funds ownership: 0.99%0.82% (-0.17%)

13% less funds holding

Funds holding: 6254 (-8)

34% less capital invested

Capital invested by funds: $8.36M → $5.54M (-$2.82M)

47% less first-time investments, than exits

New positions opened: 8 | Existing positions closed: 15

Holders
54
Holders Change
-8
Holders Change %
-12.9%
% of All Funds
0.71%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
8
Increased
20
Reduced
11
Closed
15
Calls
$4K
Puts
Net Calls
+$4K
Net Calls Change
-$1K
Name Holding Trade Value Shares
Change
Change in
Stake
PA
1
Perceptive Advisors
New York
$2.63M
BlackRock
2
BlackRock
New York
$642K +$25.6K +2,323 +4%
SB
3
Samsara BioCapital
California
$406K -$179K -16,291 -29%
Vanguard Group
4
Vanguard Group
Pennsylvania
$368K +$1.79K +163 +0.5%
IC
5
Ikarian Capital
Texas
$218K +$286 +26 +0.1%
Geode Capital Management
6
Geode Capital Management
Massachusetts
$183K +$25.9K +2,351 +15%
Goldman Sachs
7
Goldman Sachs
New York
$115K +$1.79K +163 +1%
ACM
8
ADAR1 Capital Management
Texas
$110K +$117K +10,664 New
State Street
9
State Street
Massachusetts
$101K
UBS Group
10
UBS Group
Switzerland
$87.5K +$88K +8,001 +1,607%
Two Sigma Advisers
11
Two Sigma Advisers
New York
$79.6K -$16.5K -1,496 -16%
Qube Research & Technologies (QRT)
12
Qube Research & Technologies (QRT)
United Kingdom
$70.6K +$75.3K +6,843 New
Northern Trust
13
Northern Trust
Illinois
$59.1K +$22.7K +2,060 +56%
BNP Paribas Financial Markets
14
BNP Paribas Financial Markets
France
$50.6K +$53.9K +4,898 New
BFM
15
Boothbay Fund Management
New York
$48.3K +$297 +27 +0.6%
Morgan Stanley
16
Morgan Stanley
New York
$44.7K -$95.9K -8,718 -67%
Two Sigma Investments
17
Two Sigma Investments
New York
$43.3K -$16K -1,451 -26%
JP Morgan Chase
18
JP Morgan Chase
New York
$32.3K +$21.3K +1,934 +162%
New York State Common Retirement Fund
19
New York State Common Retirement Fund
New York
$32K
Charles Schwab
20
Charles Schwab
California
$23K
Susquehanna International Group
21
Susquehanna International Group
Pennsylvania
$21.3K +$19.9K +1,811 +702%
Fidelity Investments
22
Fidelity Investments
Massachusetts
$20.6K +$13.1K +1,191 +148%
SEI Investments
23
SEI Investments
Pennsylvania
$17.4K -$201K -18,274 -92%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$15.7K
Barclays
25
Barclays
United Kingdom
$15.5K +$2.63K +239 +19%

LYRA Hedge Fund Activity: Q4 2024 in Review

54 of the 7,594 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q4 2024, worth a combined $5.54M — down 34% from $8.36M a quarter earlier.

Sellers outnumbered buyers: 15 funds closed out of LYRA and 8 opened new positions — a net loss of 7 holders — while 11 trimmed existing stakes and 20 added.

The largest buyer was ADAR1 Capital Management, opening a new position worth an estimated $117K. The largest seller was Citadel Advisors, exiting entirely with an estimated $1.05M sold.

  • 54 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q4 2024, down from 62 in Q3 2024.
  • Funds reported $5.54M of LYRA THERAPEUTICS INC stock for Q4 2024, down 34% quarter-over-quarter.
  • 8 funds opened new LYRA THERAPEUTICS INC positions in Q4 2024 and 15 closed out, a net change of -7 holders.
  • The largest LYRA THERAPEUTICS INC buyer in Q4 2024 was ADAR1 Capital Management, an estimated $117K added.
  • The largest LYRA THERAPEUTICS INC seller in Q4 2024 was Citadel Advisors, an estimated $1.05M sold.

Based on aggregated 13F filings for Q4 2024.