LYRA THERAPEUTICS INC
LYRA
LYRA was delisted on the 16th of March, 2026.
43 hedge funds and large institutions have $98M invested in LYRA THERAPEUTICS INC in 2020 Q4 according to their latest regulatory filings, with 10 funds opening new positions, 22 increasing their positions, 3 reducing their positions, and 7 closing their positions.
633% more repeat investments, than reductions
Existing positions increased: 22 | Existing positions reduced: 3
43% more first-time investments, than exits
New positions opened: 10 | Existing positions closed: 7
14% more capital invested
Capital invested by funds: $85.7M → $98M (+$12.3M)
8% more funds holding
Funds holding: 40 → 43 (+3)
7.27% more ownership
Funds ownership: 59.21% → 66.48% (+7.3%)
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
IC
Ikarian Capital
Dallas,
Texas
|
+$4.82M |
| 2 |
SCM
Soleus Capital Management
Greenwich,
Connecticut
|
+$3.89M |
| 3 |
JP Morgan Chase
New York
|
+$2.13M |
| 4 |
BlackRock
New York
|
+$640K |
| 5 |
BCM
Bridgeway Capital Management
Houston,
Texas
|
+$552K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
PVI
Pura Vida Investments
New York
|
-$2.54M |
| 2 |
Invesco
Atlanta,
Georgia
|
-$2.21M |
| 3 |
Federated Hermes
Pittsburgh,
Pennsylvania
|
-$335K |
| 4 |
Nisa Investment Advisors
St. Louis,
Missouri
|
-$181K |
| 5 |
Russell Investments Group
London,
United Kingdom
|
-$153K |
LYRA Hedge Fund Activity: Q4 2020 in Review
43 of the 5,677 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q4 2020, worth a combined $98M — up 14% from $85.7M a quarter earlier.
Buyers outnumbered sellers: 10 funds opened new LYRA positions and 7 closed out — a net gain of 3 holders — while 22 added to existing stakes and 3 trimmed.
The largest buyer was Ikarian Capital, adding an estimated $4.82M. The largest seller was Pura Vida Investments, exiting entirely with an estimated $2.54M sold.
- 43 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q4 2020, up from 40 in Q3 2020.
- Funds reported $98M of LYRA THERAPEUTICS INC stock for Q4 2020, up 14% quarter-over-quarter.
- 10 funds opened new LYRA THERAPEUTICS INC positions in Q4 2020 and 7 closed out, a net change of +3 holders.
- The largest LYRA THERAPEUTICS INC buyer in Q4 2020 was Ikarian Capital, an estimated $4.82M added.
- The largest LYRA THERAPEUTICS INC seller in Q4 2020 was Pura Vida Investments, an estimated $2.54M sold.
Based on aggregated 13F filings for Q4 2020.