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LYRA

LYRA THERAPEUTICS INC

Delisted

LYRA was delisted on the 16th of March, 2026.

43 hedge funds and large institutions have $97.9M invested in LYRA THERAPEUTICS INC in 2020 Q4 according to their latest regulatory filings, with 10 funds opening new positions, 22 increasing their positions, 3 reducing their positions, and 7 closing their positions.

New
Increased
Maintained
Reduced
Closed

633% more repeat investments, than reductions

Existing positions increased: 22 | Existing positions reduced: 3

43% more first-time investments, than exits

New positions opened: 10 | Existing positions closed: 7

14% more capital invested

Capital invested by funds: $85.7M → $97.9M (+$12.2M)

8% more funds holding

Funds holding: 4043 (+3)

0.15% more ownership

Funds ownership: 1.18%1.33% (+0.15%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

Holders
43
Holders Change
+3
Holders Change %
+7.5%
% of All Funds
0.76%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
10
Increased
22
Reduced
3
Closed
7
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
PA
1
Perceptive Advisors
New York
$36.7M
PVMCV
2
Polaris Venture Management Co V
Massachusetts
$12.6M
RCM
3
RA Capital Management
Massachusetts
$9.3M
IC
4
Ikarian Capital
Texas
$9.29M +$4.82M +8,548 +110%
ACH
5
ArrowMark Colorado Holdings
Colorado
$8.85M -$139K -246 -2%
SCM
6
Soleus Capital Management
Connecticut
$5.2M +$3.89M +6,910 +312%
BlackRock
7
BlackRock
New York
$3.01M +$640K +1,136 +27%
JP Morgan Chase
8
JP Morgan Chase
New York
$2.18M +$2.13M +3,782 +9,953%
Vanguard Group
9
Vanguard Group
Pennsylvania
$1.98M +$249K +441 +15%
BFM
10
Boothbay Fund Management
New York
$996K +$492K +874 +100%
State Street
11
State Street
Massachusetts
$885K +$362K +643 +71%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$781K +$316K +560 +69%
Northern Trust
13
Northern Trust
Illinois
$775K +$215K +382 +39%
AllianceBernstein
14
AllianceBernstein
Tennessee
$699K -$4.51K -8 -0.6%
AAA
15
Affinity Asset Advisors
New York
$570K +$563K +1,000 New
BCM
16
Bridgeway Capital Management
Texas
$559K +$552K +980 New
Millennium Management
17
Millennium Management
New York
$502K +$496K +880 New
Ensign Peak Advisors
18
Ensign Peak Advisors
Utah
$447K
PPA
19
Parametric Portfolio Associates
Washington
$415K +$166K +294 +68%
PCM
20
Pentwater Capital Management
Florida
$271K
Two Sigma Investments
21
Two Sigma Investments
New York
$257K +$254K +450 New
Bank of America
22
Bank of America
North Carolina
$246K +$31K +55 +15%
Bank of New York Mellon
23
Bank of New York Mellon
New York
$222K +$42.8K +76 +24%
Morgan Stanley
24
Morgan Stanley
New York
$162K +$152K +270 +1,929%
Charles Schwab
25
Charles Schwab
California
$162K +$160K +284 New

LYRA Hedge Fund Activity: Q4 2020 in Review

43 of the 5,652 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q4 2020, worth a combined $97.9M — up 14% from $85.7M a quarter earlier.

Buyers outnumbered sellers: 10 funds opened new LYRA positions and 7 closed out — a net gain of 3 holders — while 22 added to existing stakes and 3 trimmed.

The largest buyer was Ikarian Capital, adding an estimated $4.82M. The largest seller was Pura Vida Investments, exiting entirely with an estimated $2.54M sold.

  • 43 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q4 2020, up from 40 in Q3 2020.
  • Funds reported $97.9M of LYRA THERAPEUTICS INC stock for Q4 2020, up 14% quarter-over-quarter.
  • 10 funds opened new LYRA THERAPEUTICS INC positions in Q4 2020 and 7 closed out, a net change of +3 holders.
  • The largest LYRA THERAPEUTICS INC buyer in Q4 2020 was Ikarian Capital, an estimated $4.82M added.
  • The largest LYRA THERAPEUTICS INC seller in Q4 2020 was Pura Vida Investments, an estimated $2.54M sold.

Based on aggregated 13F filings for Q4 2020.