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LYRA

LYRA THERAPEUTICS INC
LYRA

Delisted

LYRA was delisted on the 16th of March, 2026.

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37 hedge funds and large institutions have $96M invested in LYRA THERAPEUTICS INC in 2022 Q3 according to their latest regulatory filings, with 8 funds opening new positions, 7 increasing their positions, 8 reducing their positions, and 7 closing their positions.

New
Increased
Maintained
Reduced
Closed

14% more first-time investments, than exits

New positions opened: 8 | Existing positions closed: 7

3% more funds holding

Funds holding: 36 → 37 (+1)

0.01% less ownership

Funds ownership: 1.21% → 1.2% (-0.01%)

12% less capital invested

Capital invested by funds: $109M → $96M (-$12.9M)

13% less repeat investments, than reductions

Existing positions increased: 7 | Existing positions reduced: 8

100% less funds holding in top 10

Funds holding in top 10: 1 → 0 (-1)

Holders
37
Holders Change
+1
Holders Change %
+2.78%
% of All Funds
0.64%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
8
Increased
7
Reduced
8
Closed
7
Calls
$66K
Puts
–
Net Calls
+$66K
Net Calls Change
+$66K

Top Buyers

Rank Fund Capital Flow
1
Vanguard Group
Vanguard Group
Pennsylvania
+$680K
2
Citadel Advisors
Citadel Advisors
Florida
+$220K
3
Geode Capital Management
Geode Capital Management
Massachusetts
+$156K
4
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$127K
5
Bank of New York Mellon
Bank of New York Mellon
New York
+$115K

Top Sellers

Rank Fund Capital Flow
1
NCM
Nantahala Capital Management
Connecticut
-$732K
2
Millennium Management
Millennium Management
New York
-$413K
3
PVI
Pura Vida Investments
New York
-$390K
4
CH
CVI Holdings
Delaware
-$344K
5
Two Sigma Investments
Two Sigma Investments
New York
-$76K
Name Holding Trade Value Shares
Change 		Change in
Stake
TRCT
26
Tower Research Capital (TRC)
New York
$17K +$15.4K +52 +289%
UBS Group
27
UBS Group
Switzerland
$15K +$6.51K +22 +55%
Osaic Holdings
28
Osaic Holdings
Arizona
$3K – – –
US Bancorp
29
US Bancorp
Minnesota
$3K – – –
WAM
30
Worth Asset Management
Texas
$3K – – –
S
31
SignatureFD
Georgia
$3K +$2.96K +10 New
AWM
32
Ameliora Wealth Management
Switzerland
$3K +$4.44K +15 New
Wells Fargo
33
Wells Fargo
California
$1K – – –
Royal Bank of Canada
34
Royal Bank of Canada
Ontario, Canada
$1K +$887 +3 New
BNP Paribas Financial Markets
35
BNP Paribas Financial Markets
France
$150 +$296 +1 New
CH
36
CVI Holdings
Delaware
– -$344K -1,216 Closed
Two Sigma Investments
37
Two Sigma Investments
New York
– -$76K -270 Closed
Marshall Wace
38
Marshall Wace
United Kingdom
– -$74K -259 Closed
LWANC
39
Laurel Wealth Advisors (North Carolina)
North Carolina
– -$3K -10 Closed
TWC
40
TD Waterhouse Canada
Ontario, Canada
– -$1.07K -4 Closed
CA
41
CoreCap Advisors
Michigan
– -$1K -3 Closed
1
2

LYRA Hedge Fund Activity: Q3 2022 in Review

37 of the 5,806 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q3 2022, worth a combined $96M — down 12% from $109M a quarter earlier.

Buyers outnumbered sellers: 8 funds opened new LYRA positions and 7 closed out — a net gain of 1 holder — while 7 added to existing stakes and 8 trimmed.

The largest buyer was Vanguard Group, adding an estimated $680K. The largest seller was Nantahala Capital Management, cutting an estimated $732K.

  • 37 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q3 2022, up from 36 in Q2 2022.
  • Funds reported $96M of LYRA THERAPEUTICS INC stock for Q3 2022, down 12% quarter-over-quarter.
  • 8 funds opened new LYRA THERAPEUTICS INC positions in Q3 2022 and 7 closed out, a net change of +1 holder.
  • The largest LYRA THERAPEUTICS INC buyer in Q3 2022 was Vanguard Group, an estimated $680K added.
  • The largest LYRA THERAPEUTICS INC seller in Q3 2022 was Nantahala Capital Management, an estimated $732K sold.

Based on aggregated 13F filings for Q3 2022.