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LYRA

LYRA THERAPEUTICS INC
LYRA

Delisted

LYRA was delisted on the 16th of March, 2026.

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35 hedge funds and large institutions have $60.8M invested in LYRA THERAPEUTICS INC in 2021 Q3 according to their latest regulatory filings, with 3 funds opening new positions, 7 increasing their positions, 15 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

9% more capital invested

Capital invested by funds: $55.9M → $60.8M (+$4.96M)

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

0.05% less ownership

Funds ownership: 1.07% → 1.03% (-0.05%)

20% less funds holding

Funds holding: 44 → 35 (-9)

53% less repeat investments, than reductions

Existing positions increased: 7 | Existing positions reduced: 15

75% less first-time investments, than exits

New positions opened: 3 | Existing positions closed: 12

Holders
35
Holders Change
-9
Holders Change %
-20.45%
% of All Funds
0.61%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
3
Increased
7
Reduced
15
Closed
12
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
PGM
Parian Global Management
New York
+$917K
2
Bank of America
Bank of America
North Carolina
+$601K
3
SCM
Soleus Capital Management
Connecticut
+$246K
4
BCM
Bridgeway Capital Management
Texas
+$204K
5
Two Sigma Advisers
Two Sigma Advisers
New York
+$106K

Top Sellers

Rank Fund Capital Flow
1
IC
Ikarian Capital
Texas
-$1.67M
2
William Blair & Company
William Blair & Company
Illinois
-$442K
3
Morgan Stanley
Morgan Stanley
New York
-$418K
4
BFM
Boothbay Fund Management
New York
-$332K
5
TEE
Tibra Equities Europe
United Kingdom
-$321K
Name Holding Trade Value Shares
Change 		Change in
Stake
TRCT
26
Tower Research Capital (TRC)
New York
$38K +$21.6K +57 +204%
Osaic Holdings
27
Osaic Holdings
Arizona
$12K -$24.2K -64 -72%
CCMIC
28
Cardinal Capital Management Inc (Canada)
Manitoba, Canada
$6K – – –
LWANC
29
Laurel Wealth Advisors (North Carolina)
North Carolina
$5K – – –
US Bancorp
30
US Bancorp
Minnesota
$5K – – –
Wells Fargo
31
Wells Fargo
California
$5K +$378 +1 +10%
Royal Bank of Canada
32
Royal Bank of Canada
Ontario, Canada
$3K -$756 -2 -25%
HI
33
Harbour Investments
Wisconsin
$2K – – –
Koshinski Asset Management
34
Koshinski Asset Management
Illinois
$1.82K +$1.51K +4 New
William Blair & Company
35
William Blair & Company
Illinois
– -$442K -1,100 Closed
TEE
36
Tibra Equities Europe
United Kingdom
– -$321K -800 Closed
ECM
37
ExodusPoint Capital Management
New York
– -$253K -631 Closed
Citadel Advisors
38
Citadel Advisors
Florida
– -$156K -388 Closed
Walleye Capital
39
Walleye Capital
New York
– -$153 -382 Closed
HF
40
HRT Financial
New York
– -$149K -372 Closed
Goldman Sachs
41
Goldman Sachs
New York
– -$86K -215 Closed
UBS Group
42
UBS Group
Switzerland
– -$4.16K -11 Closed
1
2

LYRA Hedge Fund Activity: Q3 2021 in Review

35 of the 5,713 institutional investors tracked by Wall St. Rank reported a position in LYRA THERAPEUTICS INC (LYRA) for Q3 2021, worth a combined $60.8M — up 8.9% from $55.9M a quarter earlier.

Sellers outnumbered buyers: 12 funds closed out of LYRA and 3 opened new positions — a net loss of 9 holders — while 15 trimmed existing stakes and 7 added.

The largest buyer was Parian Global Management, opening a new position worth an estimated $917K. The largest seller was Ikarian Capital, cutting an estimated $1.67M.

  • 35 institutional investors held LYRA THERAPEUTICS INC (LYRA) as of Q3 2021, down from 44 in Q2 2021.
  • Funds reported $60.8M of LYRA THERAPEUTICS INC stock for Q3 2021, up 8.9% quarter-over-quarter.
  • 3 funds opened new LYRA THERAPEUTICS INC positions in Q3 2021 and 12 closed out, a net change of -9 holders.
  • The largest LYRA THERAPEUTICS INC buyer in Q3 2021 was Parian Global Management, an estimated $917K added.
  • The largest LYRA THERAPEUTICS INC seller in Q3 2021 was Ikarian Capital, an estimated $1.67M sold.

Based on aggregated 13F filings for Q3 2021.