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Disc Medicine

203 hedge funds and large institutions have $2.67B invested in Disc Medicine in 2026 Q1 according to their latest regulatory filings, with 48 funds opening new positions, 80 increasing their positions, 44 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

365% more call options, than puts

Call options by funds: $23.3M | Put options by funds: $5.01M

82% more repeat investments, than reductions

Existing positions increased: 80 | Existing positions reduced: 44

26% more first-time investments, than exits

New positions opened: 48 | Existing positions closed: 38

8.37% more ownership

Funds ownership: 101.43%109.8% (+8.4%)

4% more funds holding

Funds holding: 196203 (+7)

12% less capital invested

Capital invested by funds: $3.04B → $2.67B (-$369M)

45% less funds holding in top 10

Funds holding in top 10: 116 (-5)

Holders
203
Holders Change
+7
Holders Change %
+3.57%
% of All Funds
2.5%
Holding in Top 10
6
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-45.45%
% of All Funds
0.07%
New
48
Increased
80
Reduced
44
Closed
38
Calls
$23.3M
Puts
$5.01M
Net Calls
+$18.3M
Net Calls Change
+$24.9M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$357M +$9.48M +136,672 +3%
RCM
2
RA Capital Management
Massachusetts
$157M +$32.9M +474,089 +24%
BlackRock
3
BlackRock
New York
$145M -$79.7K -1,149 -0.1%
Wellington Management Group
4
Wellington Management Group
Massachusetts
$111M +$15.1M +217,102 +14%
State Street
5
State Street
Massachusetts
$109M +$35.4M +510,253 +43%
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$99.1M -$10.3M -148,655 -9%
AVLSA
7
Atlas Venture Life Science Advisors
Massachusetts
$96.8M
VCM
8
Vanguard Capital Management
Pennsylvania
$87.9M +$95.5M +1,375,430 New
FLSM
9
Frazier Life Sciences Management
California
$86.6M +$6.58M +94,852 +8%
TCM
10
TCG Crossover Management
California
$85.8M +$93.1M +1,341,862 New
JP Morgan Chase
11
JP Morgan Chase
New York
$83.4M -$14.5M -209,647 -13%
BI
12
BVF Inc
California
$81.4M +$43.2M +622,312 +96%
O
13
OrbiMed
New York
$68.3M
SL
14
Siren LLC
Connecticut
$63.2M
WP
15
Woodline Partners
California
$61.3M +$31.1K +448 +0%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$47.6M +$4.11M +59,264 +9%
VPC
17
Vestal Point Capital
New York
$44.8M -$2.43M -35,000 -5%
DM
18
Deerfield Management
New York
$42M +$10.1M +145,837 +29%
Goldman Sachs
19
Goldman Sachs
New York
$40.9M -$7.94M -114,353 -15%
Jennison Associates
20
Jennison Associates
New York
$39M +$5.43M +78,303 +15%
LGM
21
Logos Global Management
California
$35.8M +$3.47M +50,000 +10%
Assenagon Asset Management
22
Assenagon Asset Management
Luxembourg
$34.9M +$13.1M +188,411 +53%
AC
23
Armistice Capital
New York
$34.3M +$2.54M +36,609 +7%
BG
24
Bellevue Group
Switzerland
$29.4M +$31.9M +459,314 New
SVCM
25
Saturn V Capital Management
Texas
$28.8M +$10.5M +151,497 +51%

IRON Hedge Fund Activity: Q1 2026 in Review

203 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q1 2026, worth a combined $2.67B — down 12% from $3.04B a quarter earlier.

Buyers outnumbered sellers: 48 funds opened new IRON positions and 38 closed out — a net gain of 10 holders — while 80 added to existing stakes and 44 trimmed.

The largest buyer was TCG Crossover Management, opening a new position worth an estimated $93.1M. The largest seller was First Light Asset Management, exiting entirely with an estimated $41.5M sold.

  • 203 institutional investors held Disc Medicine (IRON) as of Q1 2026, up from 196 in Q4 2025.
  • Funds reported $2.67B of Disc Medicine stock for Q1 2026, down 12% quarter-over-quarter.
  • 48 funds opened new Disc Medicine positions in Q1 2026 and 38 closed out, a net change of +10 holders.
  • The largest Disc Medicine buyer in Q1 2026 was TCG Crossover Management, an estimated $93.1M added.
  • The largest Disc Medicine seller in Q1 2026 was First Light Asset Management, an estimated $41.5M sold.

Based on aggregated 13F filings for Q1 2026.