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Disc Medicine
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Overview Fund Activity

91 hedge funds and large institutions have $934M invested in Disc Medicine in 2023 Q3 according to their latest regulatory filings, with 19 funds opening new positions, 39 increasing their positions, 19 reducing their positions, and 18 closing their positions.

Holders
91
Holders Change
+1
Holders Change %
+1.11%
% of All Funds
1.45%
Holding in Top 10
8
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.13%
New
19
Increased
39
Reduced
19
Closed
18
Calls
$4.42M
Puts
$9.95M
Net Calls
-$5.53M
Net Calls Change
-$1.9B

Top Buyers

1
PBA
1
Paradigm Biocapital Advisors
New York
$59.8M
2
PCH
2
Polar Capital Holdings
United Kingdom
$25.7M
3
State Street
3
State Street
Massachusetts
$31.3M
4
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$24.8M
5
PA
5
Perceptive Advisors
New York
$42.1M

Top Sellers

1
AVLSA
1
Atlas Venture Life Science Advisors
Massachusetts
$129M
2
Bank of America
2
Bank of America
North Carolina
$2.53M
3
OCA
3
Octagon Capital Advisors
New York
$0
4
Citadel Advisors
4
Citadel Advisors
Florida
$14.6M
5
Assenagon Asset Management
5
Assenagon Asset Management
Luxembourg
$3.48M
Name Market Value Shares Shares
Change 		Shares
Change %
AVLSA
1
Atlas Venture Life Science Advisors
Massachusetts
$129M 2,745,335 -716,449 -21%
O
2
OrbiMed
New York
$107M 2,269,637 – –
BCLSI
3
Bain Capital Life Sciences Investors
Massachusetts
$62.6M 1,332,545 -3 -0%
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$61.5M 1,308,405 +145,781 +13%
PBA
5
Paradigm Biocapital Advisors
New York
$59.8M 1,272,279 +1,272,279 New
NHAS
6
Novo Holdings A/S
Denmark
$51.2M 1,090,772 – –
PA
7
Perceptive Advisors
New York
$42.1M 895,641 +152,803 +21%
State Street
8
State Street
Massachusetts
$31.3M 667,301 +527,898 +379%
Vanguard Group
9
Vanguard Group
Pennsylvania
$31.3M 665,452 +105,685 +19%
FLSM
10
Frazier Life Sciences Management
California
$30.8M 655,000 – –
BlackRock
11
BlackRock
New York
$30.3M 644,331 +141,782 +28%
PCH
12
Polar Capital Holdings
United Kingdom
$25.7M 546,915 +546,915 New
T. Rowe Price Associates
13
T. Rowe Price Associates
Maryland
$24.8M 527,739 +325,069 +160%
Janus Henderson Group
14
Janus Henderson Group
United Kingdom
$23.5M 500,380 +1 +0%
5VM
15
5AM Venture Management
California
$20.6M 438,442 -50,000 -10%
DM
16
Deerfield Management
New York
$20.2M 430,000 – –
RSCM
17
Rock Springs Capital Management
Maryland
$17.1M 363,468 – –
Citadel Advisors
18
Citadel Advisors
Florida
$14.6M 310,431 -340,889 -52%
Fidelity Investments
19
Fidelity Investments
Massachusetts
$14.3M 305,433 -17,621 -5%
FCMV
20
Foresite Capital Management V
California
$11.4M 243,513 – –
CAM
21
Cormorant Asset Management
Massachusetts
$10.6M 225,000 – –
Geode Capital Management
22
Geode Capital Management
Massachusetts
$10.1M 214,398 +67,343 +46%
Invesco
23
Invesco
Georgia
$7.57M 161,213 +50,581 +46%
Franklin Resources
24
Franklin Resources
California
$7.56M 161,021 +3,766 +2%
IC
25
Ikarian Capital
Texas
$6.71M 142,766 -97,265 -41%
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