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Disc Medicine
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Overview Fund Activity

130 hedge funds and large institutions have $1.38B invested in Disc Medicine in 2024 Q1 according to their latest regulatory filings, with 31 funds opening new positions, 57 increasing their positions, 29 reducing their positions, and 12 closing their positions.

Holders
130
Holders Change
+18
Holders Change %
+16.07%
% of All Funds
1.88%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.07%
New
31
Increased
57
Reduced
29
Closed
12
Calls
$22.1M
Puts
$68.3M
Net Calls
-$46.2M
Net Calls Change
-$49M

Top Buyers

1
State Street
1
State Street
Massachusetts
$67.9M
2
Wellington Management Group
2
Wellington Management Group
Massachusetts
$41.7M
3
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$58.8M
4
DM
4
Deerfield Management
New York
$41.4M
5
SVCM
5
Saturn V Capital Management
Texas
$15.9M

Top Sellers

1
PCH
1
Polar Capital Holdings
United Kingdom
$15.2M
2
5VM
2
5AM Venture Management
California
$0
3
AVLSA
3
Atlas Venture Life Science Advisors
Massachusetts
$142M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$35.8M
5
IC
5
Ikarian Capital
Texas
$1.58M
Name Market Value Shares Shares
Change 		Shares
Change %
PBA
1
Paradigm Biocapital Advisors
New York
$149M 2,389,902 +4,045 +0.2%
AVLSA
2
Atlas Venture Life Science Advisors
Massachusetts
$142M 2,287,233 -267,939 -10%
O
3
OrbiMed
New York
$106M 1,702,237 – –
BCLSI
4
Bain Capital Life Sciences Investors
Massachusetts
$82M 1,317,213 -15,332 -1%
State Street
5
State Street
Massachusetts
$67.9M 1,091,211 +532,016 +95%
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$58.8M 944,213 +353,382 +60%
PA
7
Perceptive Advisors
New York
$58.5M 939,866 -83,179 -8%
BlackRock
8
BlackRock
New York
$56.1M 901,595 +33,155 +4%
FLSM
9
Frazier Life Sciences Management
California
$48.9M 785,000 – –
Vanguard Group
10
Vanguard Group
Pennsylvania
$48.7M 782,751 +18,207 +2%
Wellington Management Group
11
Wellington Management Group
Massachusetts
$41.7M 670,482 +492,756 +277%
DM
12
Deerfield Management
New York
$41.4M 665,535 +201,243 +43%
Adage Capital Partners
13
Adage Capital Partners
Massachusetts
$35.8M 574,464 -175,536 -23%
Janus Henderson Group
14
Janus Henderson Group
United Kingdom
$32.5M 521,773 +78,595 +18%
AllianceBernstein
15
AllianceBernstein
Tennessee
$30.9M 496,881 +133,796 +37%
Fidelity Investments
16
Fidelity Investments
Massachusetts
$25.1M 403,532 +186,120 +86%
RSCM
17
Rock Springs Capital Management
Maryland
$22.6M 363,468 – –
Citadel Advisors
18
Citadel Advisors
Florida
$20.3M 325,724 +137,800 +73%
SVCM
19
Saturn V Capital Management
Texas
$15.9M 254,803 +190,019 +293%
FTM
20
First Turn Management
California
$15.7M 252,673 +95,399 +61%
Geode Capital Management
21
Geode Capital Management
Massachusetts
$15.3M 245,774 +16,355 +7%
PCH
22
Polar Capital Holdings
United Kingdom
$15.2M 244,928 -301,987 -55%
FCMV
23
Foresite Capital Management V
California
$15.2M 243,513 – –
Pictet Asset Management
24
Pictet Asset Management
Switzerland
$14.4M 231,797 +36,706 +19%
Bank of America
25
Bank of America
North Carolina
$13.3M 213,691 +181,731 +569%
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