State Street
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State Street’s Disc Medicine IRON Stock Holding History

State Street’s Portfolio IRON Stock Details IRON Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$121M Sell
1,648,836
-49,408
-3% -$3.4M ﹤0.01% 1366
2026
Q1 		$109M Buy
1,698,244
+510,253
+43% +$35.4M ﹤0.01% 1331
2025
Q4 		$94.3M Buy
1,187,991
+142,394
+14% +$12M ﹤0.01% 1397
2025
Q3 		$69.1M Buy
1,045,597
+115,829
+12% +$6.89M ﹤0.01% 1565
2025
Q2 		$49.2M Buy
929,768
+11,201
+1% +$526K ﹤0.01% 1689
2025
Q1 		$45.6M Buy
918,567
+149,832
+19% +$8.33M ﹤0.01% 1694
2024
Q4 		$48.7M Sell
768,735
-59,175
-7% -$3.42M ﹤0.01% 1731
2024
Q3 		$40.7M Buy
827,910
+235,115
+40% +$11M ﹤0.01% 1805
2024
Q2 		$26.7M Sell
592,795
-498,416
-46% -$16.9M ﹤0.01% 2016
2024
Q1 		$67.9M Buy
1,091,211
+532,016
+95% +$34.5M ﹤0.01% 1547
2023
Q4 		$32.3M Sell
559,195
-108,106
-16% -$5.54M ﹤0.01% 1932
2023
Q3 		$31.3M Buy
667,301
+527,898
+379% +$26.4M ﹤0.01% 1895
2023
Q2 		$6.19M Buy
139,403
+124,916
+862% +$4.43M ﹤0.01% 2897
2023
Q1 		$307K Buy
14,487
+4,298
+42% +$95.8K ﹤0.01% 3921
2022
Q4 		$203K Buy
10,189
+6,792
+200% +$338K ﹤0.01% 4092
2022
Q3 		$167K Hold
3,397
– – ﹤0.01% 4219
2022
Q2 		$172K Sell
3,397
-10,226
-75% -$452K ﹤0.01% 4275
2022
Q1 		$568K Sell
13,623
-118
-0.9% -$6.19K ﹤0.01% 3992
2021
Q4 		$1.2M Sell
13,741
-103
-0.7% -$10.1K ﹤0.01% 3772
2021
Q3 		$1.68M Buy
13,844
+3,573
+35% +$488K ﹤0.01% 3658
2021
Q2 		$1.99M Buy
10,271
+9,644
+1,538% +$3.17M ﹤0.01% 3549
2021
Q1 		$255K Buy
+627
New +$280K ﹤0.01% 3811

Other funds holding IRON

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $580B AUM 38.23% 1-Year Est. Return
VPC
Vestal Point Capital New York $4.28B AUM 239% 1-Year Est. Return
AVLSA
Atlas Venture Life Science Advisors Cambridge, Massachusetts $881M AUM 160.77% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
FLSM
Frazier Life Sciences Management Palo Alto, California $4.59B AUM 237.58% 1-Year Est. Return

State Street's IRON Position: Q2 2026 in Review

State Street reduced its Disc Medicine (IRON) stake by 2.9% in Q2 2026, selling an estimated $3.4M and leaving 1,648,836 shares worth $121M. The position accounts for ﹤0.01% of the portfolio, ranked #1366.

State Street first reported a position in IRON in Q1 2021 and has held it in 22 quarters since. 216 funds tracked by Wall St. Rank hold IRON as of Q2 2026.

  • State Street held 1,648,836 shares of Disc Medicine worth $121M as of Q2 2026.
  • State Street sold 49,408 Disc Medicine shares in Q2 2026, an estimated $3.4M.
  • Disc Medicine made up ﹤0.01% of State Street's portfolio in Q2 2026, its #1366 holding.
  • State Street first reported a position in Disc Medicine in Q1 2021 and has held it in 22 quarters since.
  • 216 funds tracked by Wall St. Rank held Disc Medicine as of Q2 2026.

Based on State Street's 13F filing for Q2 2026, filed 7 Aug 2026.