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Disc Medicine
IRON

57 hedge funds and large institutions have $39.6M invested in Disc Medicine in 2022 Q1 according to their latest regulatory filings, with 8 funds opening new positions, 13 increasing their positions, 23 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

0.3% less ownership

Funds ownership: 2.49% → 2.2% (-0.3%)

8% less funds holding

Funds holding: 62 → 57 (-5)

38% less first-time investments, than exits

New positions opened: 8 | Existing positions closed: 13

43% less repeat investments, than reductions

Existing positions increased: 13 | Existing positions reduced: 23

58% less capital invested

Capital invested by funds: $93.8M → $39.6M (-$54.2M)

Holders
57
Holders Change
-5
Holders Change %
-8.06%
% of All Funds
0.9%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
8
Increased
13
Reduced
23
Closed
13
Calls
$27K
Puts
–
Net Calls
+$27K
Net Calls Change
-$123K

Top Buyers

Rank Fund Capital Flow
1
Renaissance Technologies
Renaissance Technologies
New York
+$593K
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$350K
3
Allspring Global Investments
Allspring Global Investments
North Carolina
+$173K
4
MAM
Marquette Asset Management
Minnesota
+$116K
5
CM
Crestline Management
Texas
+$109K

Top Sellers

Rank Fund Capital Flow
1
Fidelity Investments
Fidelity Investments
Massachusetts
-$2.6M
2
Franklin Resources
Franklin Resources
California
-$2.52M
3
Alyeska Investment Group
Alyeska Investment Group
Illinois
-$1.85M
4
JCM
JS Capital Management
New York
-$1.38M
5
Vanguard Group
Vanguard Group
Pennsylvania
-$573K
Name Holding Trade Value Shares
Change 		Change in
Stake
O
1
OrbiMed
New York
$8.1M – – –
AVLSA
2
Atlas Venture Life Science Advisors
Massachusetts
$7.3M – – –
FCMV
3
Foresite Capital Management V
California
$3.38M – – –
FCOMV
4
Foresite Capital Opportunity Management V
California
$3.38M – – –
SCM
5
Suvretta Capital Management
New York
$3.3M – – –
BC
6
Boxer Capital
California
$1.81M – – –
BlackRock
7
BlackRock
New York
$1.81M +$76.6K +1,461 +3%
Franklin Resources
8
Franklin Resources
California
$1.49M -$2.52M -48,033 -57%
Adage Capital Partners
9
Adage Capital Partners
Massachusetts
$1.23M +$350K +6,666 +29%
Vanguard Group
10
Vanguard Group
Pennsylvania
$1.03M -$573K -10,929 -31%
Millennium Management
11
Millennium Management
New York
$745K +$50.4K +962 +6%
PVI
12
Pura Vida Investments
New York
$690K +$5.4K +103 +0.6%
IC
13
Ikarian Capital
Texas
$615K +$38.5K +735 +5%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$599K -$20.3K -388 -3%
State Street
15
State Street
Massachusetts
$568K -$6.19K -118 -0.9%
Fidelity Investments
16
Fidelity Investments
Massachusetts
$551K -$2.6M -49,663 -79%
Renaissance Technologies
17
Renaissance Technologies
New York
$488K +$593K +11,306 +2,848%
Citadel Advisors
18
Citadel Advisors
Florida
$474K +$10.7K +205 +2%
HMC
19
Harvard Management Company
Massachusetts
$348K – – –
Northern Trust
20
Northern Trust
Illinois
$272K -$9.91K -189 -3%
BCM
21
Bridgeway Capital Management
Texas
$163K – – –
Allspring Global Investments
22
Allspring Global Investments
North Carolina
$160K +$173K +3,298 +608%
Stifel Financial
23
Stifel Financial
Missouri
$144K +$66.3K +1,264 +58%
N
24
Nuveen
North Carolina
$116K +$6.03K +115 +4%
Bank of New York Mellon
25
Bank of New York Mellon
New York
$96K -$2.88K -55 -2%
1
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IRON Hedge Fund Activity: Q1 2022 in Review

57 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q1 2022, worth a combined $39.6M — down 58% from $93.8M a quarter earlier.

Sellers outnumbered buyers: 13 funds closed out of IRON and 8 opened new positions — a net loss of 5 holders — while 23 trimmed existing stakes and 13 added.

The largest buyer was Renaissance Technologies, adding an estimated $593K. The largest seller was Fidelity Investments, cutting an estimated $2.6M.

  • 57 institutional investors held Disc Medicine (IRON) as of Q1 2022, down from 62 in Q4 2021.
  • Funds reported $39.6M of Disc Medicine stock for Q1 2022, down 58% quarter-over-quarter.
  • 8 funds opened new Disc Medicine positions in Q1 2022 and 13 closed out, a net change of -5 holders.
  • The largest Disc Medicine buyer in Q1 2022 was Renaissance Technologies, an estimated $593K added.
  • The largest Disc Medicine seller in Q1 2022 was Fidelity Investments, an estimated $2.6M sold.

Based on aggregated 13F filings for Q1 2022.