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Disc Medicine

35 hedge funds and large institutions have $216M invested in Disc Medicine in 2022 Q4 according to their latest regulatory filings, with 8 funds opening new positions, 24 increasing their positions, 3 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

700% more repeat investments, than reductions

Existing positions increased: 24 | Existing positions reduced: 3

529% more capital invested

Capital invested by funds: $34.3M → $216M (+$181M)

150% more funds holding in top 10

Funds holding in top 10: 25 (+3)

24.34% more ownership

Funds ownership: 2.06%26.4% (+24%)

20% less funds holding

Funds holding: 4435 (-9)

50% less first-time investments, than exits

New positions opened: 8 | Existing positions closed: 16

Holders
35
Holders Change
-9
Holders Change %
-20.45%
% of All Funds
0.56%
Holding in Top 10
5
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+150%
% of All Funds
0.08%
New
8
Increased
24
Reduced
3
Closed
16
Calls
$2.05M
Puts
Net Calls
+$2.05M
Net Calls Change
+$1.99M
Name Holding Trade Value Shares
Change
Change in
Stake
AVLSA
1
Atlas Venture Life Science Advisors
Massachusetts
$68.9M +$164M +3,286,638 +1,877%
NHAS
2
Novo Holdings A/S
Denmark
$46.6M +$117M +2,340,772 New
O
3
OrbiMed
New York
$43M +$97.9M +1,966,734 +1,013%
5VM
4
5AM Venture Management
California
$11.7M +$28.4M +570,959 +3,266%
BCM
5
BML Capital Management
Indiana
$9.95M +$24.9M +500,000 New
Adage Capital Partners
6
Adage Capital Partners
Massachusetts
$6.96M +$13.4M +268,479 +329%
RSCM
7
Rock Springs Capital Management
Maryland
$6.75M +$16.9M +339,497 New
FCMV
8
Foresite Capital Management V
California
$4.84M +$8.08M +162,342 +200%
Fidelity Investments
9
Fidelity Investments
Massachusetts
$3.84M +$8.97M +180,085 +1,369%
NCM
10
Nantahala Capital Management
Connecticut
$3.06M +$7.68M +154,173 +1,795%
TOCUITCONY
11
Trustees of Columbia University in the City of New York
New York
$2.2M +$5.5M +110,488 New
Assenagon Asset Management
12
Assenagon Asset Management
Luxembourg
$1.36M +$3.27M +65,687 +2,398%
Vanguard Group
13
Vanguard Group
Pennsylvania
$1.11M +$1.86M +37,263 +200%
Citadel Advisors
14
Citadel Advisors
Florida
$1.11M +$1.81M +36,348 +188%
Janus Henderson Group
15
Janus Henderson Group
United Kingdom
$982K +$24.9M +500,330 New
ECM
16
ExodusPoint Capital Management
New York
$601K +$1.42M +28,506 +1,652%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$540K +$901K +18,084 +199%
HMC
18
Harvard Management Company
Massachusetts
$497K +$830K +16,667 +200%
BlackRock
19
BlackRock
New York
$399K +$667K +13,397 +200%
Millennium Management
20
Millennium Management
New York
$294K +$166K +3,343 +29%
Stifel Financial
21
Stifel Financial
Missouri
$273K +$456K +9,148 +200%
Renaissance Technologies
22
Renaissance Technologies
New York
$258K +$347K +6,975 +116%
State Street
23
State Street
Massachusetts
$203K +$338K +6,792 +200%
BC
24
Boxer Capital
California
$176K +$4.32M +86,667 +200%
UBS Group
25
UBS Group
Switzerland
$142K +$252K +5,052 +245%

IRON Hedge Fund Activity: Q4 2022 in Review

35 of the 6,222 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q4 2022, worth a combined $216M — up 529% from $34.3M a quarter earlier.

Sellers outnumbered buyers: 16 funds closed out of IRON and 8 opened new positions — a net loss of 8 holders — while 3 trimmed existing stakes and 24 added.

The largest buyer was Atlas Venture Life Science Advisors, adding an estimated $164M. The largest seller was Suvretta Capital Management, exiting entirely with an estimated $3.89M sold.

  • 35 institutional investors held Disc Medicine (IRON) as of Q4 2022, down from 44 in Q3 2022.
  • Funds reported $216M of Disc Medicine stock for Q4 2022, up 529% quarter-over-quarter.
  • 8 funds opened new Disc Medicine positions in Q4 2022 and 16 closed out, a net change of -8 holders.
  • The largest Disc Medicine buyer in Q4 2022 was Atlas Venture Life Science Advisors, an estimated $164M added.
  • The largest Disc Medicine seller in Q4 2022 was Suvretta Capital Management, an estimated $3.89M sold.

Based on aggregated 13F filings for Q4 2022.